Introduction Cytarabine is one of the main chemotherapy drugs used to treat hematological
malignancies. Neurotoxicity is an increasingly recognized adverse effect of high-dose …

Cytarabine is a pyrimidine analogue that is used for the treatment of acute myeloid leukemia
at different doses. Standard doses of cytarabine are used for induction therapy, while high …

High-dose arabinoside cytarabine is used as an effective regimen for post-remission acute
leukemia and refractory leukemia treatment. Most commonly used regimen is 3 g/m2 IV over …

Neurotoxicity from high-dose cytarabine, a pyrimidine metabolite used in treatment for acute
myeloid leukemia, is a known but dose-limiting toxicity which has incidences in up to 14% in …

Cytarabine is a chemotherapy agent that has various side effects, including neurotoxicity. In
the last 15 years, several case reports show various neurotoxic symptoms caused by …

Acute cerebellar toxicity with ataxia and dysarthria is a well-known side effect during high-
dose cytarabine therapy. Dose, age, previous neurological disorders, hepatic dysfunction …

Objective Neurotoxicity is a well-recognized complication of high-dose cytosine arabinoside
(HIDAC). We describe a patient with AML who suffered cerebellar toxicity following high …

Cytarabine is an effective drug in the treatment of certain hematologic malignancies and its
common toxicities are myelosuppression and gastrointestinal disturbance. In the past …

High-dose cytarabine (HDARAC) therapy is an effective regimen in treating refractory
leukemias. A typical regimen is cytarabine 3 g/m2 iv over one to three hours q 12h for a total …

Patients undergoing standard treat-ment for acute leukemia typically receive high-dose
cytarabine as part of their induction and consolidation regimens. Cytarabine, also known as …