[HTML][HTML] Natural products: evidence for neuroprotection to be exploited in glaucoma

A Adornetto, L Rombolà, LA Morrone, C Nucci… - Nutrients, 2020 - mdpi.com
Glaucoma, a leading cause of irreversible blindness worldwide, is an optic neuropathy
characterized by the progressive death of retinal ganglion cells (RGCs). Elevated intraocular …

Rational basis for nutraceuticals in the treatment of glaucoma

ML Antonio, R Laura, A Annagrazia… - Current …, 2018 - ingentaconnect.com
Background: Glaucoma, the second leading cause of blindness worldwide, is a chronic optic
neuropathy characterized by progressive retinal ganglion cell (RGC) axons degeneration …

Natural compounds: evidence for a protective role in eye disease

R Ritch - Canadian Journal of Ophthalmology, 2007 - Elsevier
Glaucoma often progresses despite lowering of intraocular pressure (IOP) to acceptable or
normal levels; it can also develop at normal or even low IOP on the basis of non-IOP …

Natural compounds and retinal ganglion cell neuroprotection

LA Morrone, L Rombolà, MT Corasaniti… - Progress in brain …, 2015 - Elsevier
Glaucoma, the second leading cause of blindness in the world, is a chronic optic neuropathy
often associated with increased intraocular pressure and characterized by progressive …

[HTML][HTML] Treatment of glaucoma with natural products and their mechanism of action: An update

RH Sim, SR Sirasanagandla, S Das, SL Teoh - Nutrients, 2022 - mdpi.com
Glaucoma is one of the leading causes of irreversible blindness. It is generally caused by
increased intraocular pressure, which results in damage of the optic nerve and retinal …

Non-drug interventions in glaucoma: Putative roles for lifestyle, diet and nutritional supplements

F Fahmideh, N Marchesi, A Barbieri, S Govoni… - Survey of …, 2022 - Elsevier
Glaucoma is a major ocular neurodegenerative disease characterized by progressive retinal
ganglion cells degeneration and sight loss. Current treatment options have been limited to …

[HTML][HTML] Protective efficacy of a dietary supplement based on forskolin, homotaurine, spearmint extract, and group B vitamins in a mouse model of optic nerve injury

F Locri, M Cammalleri, M Dal Monte, D Rusciano… - Nutrients, 2019 - mdpi.com
Glaucoma is a multifactorial blinding disease with a major inflammatory component
ultimately leading to apoptotic retinal ganglion cell (RGC) death. Pharmacological …

Impact of nutraceuticals on glaucoma: A systematic review

D Scuteri, L Rombola, C Watanabe, S Sakurada… - Progress in brain …, 2020 - Elsevier
Background: glaucoma is a remarkable social issue being the leading cause of irreversible
blindness worldwide. It is a progressive neuropathy characterized by the death of the retinal …

[HTML][HTML] Substances of interest that support glaucoma therapy

SC Saccà, P Corazza, S Gandolfi, D Ferrari, S Sukkar… - Nutrients, 2019 - mdpi.com
Glaucoma is a multifactorial disease in which pro-apoptotic signals are directed to retinal
ganglion cells. During this disease the conventional outflow pathway becomes …

[HTML][HTML] Neuroprotective agents in the management of glaucoma

C Nucci, A Martucci, C Giannini, LA Morrone, G Bagetta… - Eye, 2018 - nature.com
Glaucoma is an optic neuropathy, specifically a neurodegenerative disease characterized
by loss of retinal ganglion cells (RGCs) and their axons. The pathogenesis of RGC loss in …