Manufacturing methods, properties, and potential applications in bone tissue regeneration of hydroxyapatite-chitosan biocomposites: A review

HA Said, H Mabroum, M Lahcini, H Oudadesse… - International Journal of …, 2023 - Elsevier
Hydroxyapatite (HA) and chitosan (CS) biopolymer are the major materials investigated for
biomedical purposes. Both of these components play an important role in the orthopedic …

Development and characterization of hydroxyapatite/β-TCP/chitosan composites for tissue engineering applications

A Shavandi, AEDA Bekhit, MA Ali, Z Sun… - Materials Science and …, 2015 - Elsevier
Calcium phosphate ceramics that mimic bone composition provide interesting possibilities
for the advancement in bone tissue engineering. The present study reports on a chitosan …

Biocomposites containing natural polymers and hydroxyapatite for bone tissue engineering

M Swetha, K Sahithi, A Moorthi, N Srinivasan… - International journal of …, 2010 - Elsevier
Bone tissue engineering is an alternative strategy to generate bone utilizing a combination
of biomaterials and cells. Biomaterials that mimic the structure and composition of bone …

[HTML][HTML] Preparation and characterization of homogeneous hydroxyapatite/chitosan composite scaffolds via in-situ hydration

H Li, CR Zhou, MY Zhu, JH Tian, JH Rong - Journal of Biomaterials and …, 2010 - scirp.org
Hydroxyapatite (HAP)/Chitosan (CS) composite is a biocompatible and bioactive material for
tissue engineering. A novel homogeneous HAP/CS composite scaffold was developed via …

[PDF][PDF] Chitosan/hydroxyapatite-based composites

C Peniche, Y Solís, N Davidenko… - Biotecnol Apl, 2010 - elfosscientiae.cigb.edu.cu
In the past 20 years, there has been a growing trend towards the development and use of
biomaterials for the repairing and restoration of damaged bone tissue. The calcium …

Biomimetic properties of an injectable chitosan/nano-hydroxyapatite/collagen composite

Z Huang, Q Feng, B Yu, S Li - Materials Science and Engineering: C, 2011 - Elsevier
To meet the challenges of designing an injectable scaffold and regenerating bone with
complex three-dimensional (3D) structures, a biomimetic and injectable hydrogel scaffold …

Biomimetic chitosan–nanohydroxyapatite composite scaffolds for bone tissue engineering

WW Thein-Han, RDK Misra - Acta biomaterialia, 2009 - Elsevier
We describe a comparative assessment of the structure–property–process relationship of
three-dimensional chitosan–nanohydroxyapatite (nHA) and pure chitosan scaffolds in …

Chitosan/hydroxyapatite hybrid scaffold for bone tissue engineering

V Brun, C Guillaume, S Mechiche Alami… - Bio-medical …, 2014 - content.iospress.com
BACKGROUND: To favor regeneration following critical bone defect, a combination of
autologous bone graft and biomaterials is currently used. Major drawbacks of such …

Synthesis and characterization of a nano‐hydroxyapatite/chitosan/polyethylene glycol nanocomposite for bone tissue engineering

M Shakir, R Jolly, MS Khan, N Iram… - Polymers for …, 2015 - Wiley Online Library
A novel nanocomposite involving nano‐hydroxyapatite/chitosan/polyethylene glycol (n‐
HAP/CS/PEG) has been successfully synthesized via co‐precipitation approach at room …

A study on the bioactivity of chitosan/nano-hydroxyapatite composite scaffolds for bone tissue engineering

L Kong, Y Gao, G Lu, Y Gong, N Zhao… - European Polymer …, 2006 - Elsevier
In order to increase the biocompatibility and bioactivity of chitosan, hydroxyapatite had been
in situ combined into chitosan scaffolds. The bioactivity of the composite scaffolds was …