Altered brain structure in chronic visceral pain: Specific differences in gray matter volume and associations with visceral symptoms and chronic stress

H Öhlmann, LR Koenen, F Labrenz, H Engler… - Frontiers in …, 2021 - frontiersin.org
Structural brain alterations in chronic pain conditions remain incompletely understood,
especially in chronic visceral pain. Patients with chronic-inflammatory or functional bowel …

Structural imaging changes and behavioral correlates in patients with Crohn's disease in remission

VA Nair, P Beniwal-Patel, I Mbah, BM Young… - Frontiers in Human …, 2016 - frontiersin.org
Background: Crohn's disease (CD) is a subtype of inflammatory bowel disease caused by
immune-mediated inflammation in the gastrointestinal tract. The extent of morphologic brain …

[HTML][HTML] Structural brain lesions in inflammatory bowel disease

C Dolapcioglu, H Dolapcioglu - World Journal of Gastrointestinal …, 2015 - ncbi.nlm.nih.gov
Central nervous system (CNS) complications or manifestations of inflammatory bowel
disease deserve particular attention because symptomatic conditions can require early …

Inflammatory bowel disease: perspectives from cingulate cortex in the first brain

BA Vogt - Neurogastroenterology & Motility, 2013 - Wiley Online Library
The article by Agostini et al.(2013) in this issue of Neurogastroenterology and Motility
evaluated patients with Crohn's disease (CD) for volumetric changes throughout the brain …

Brain resting-state network alterations associated with Crohn's disease

J Kornelsen, A Wilson, JS Labus, K Witges… - Frontiers in …, 2020 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic disease that is associated with aspects of
brain anatomy and activity. In this preliminary MRI study, we investigated differences in brain …

Altered viscerotopic cortical innervation in patients with irritable bowel syndrome

A Irimia, JS Labus, CM Torgerson… - …, 2015 - Wiley Online Library
Background Studies have demonstrated the existence of regional gray matter and white
matter (WM) alterations in the brains of patients with irritable bowel syndrome (IBS), but the …

Alterations in brain white matter microstructural properties in patients with Crohn's disease in remission

J Hou, K Dodd, VA Nair, S Rajan, P Beniwal-Patel… - Scientific reports, 2020 - nature.com
Patients with inflammatory bowel disease have been shown to have abnormal brain
morphometry or function, which are associated with psychological symptoms such as stress …

Altered markers of brain development in Crohn's Disease with extraintestinal manifestations–a pilot study

AK Thomann, PA Thomann, RC Wolf, D Hirjak… - PloS one, 2016 - journals.plos.org
Background and Objective Alterations of brain morphology in Crohn's disease have been
reported, but data is scarce and heterogenous and the possible impact of disease …

Regional gray matter density changes in brains of patients with irritable bowel syndrome

DA Seminowicz, JS Labus, JA Bueller, K Tillisch… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Several studies have examined structural brain changes
associated with chronic pain syndromes, including irritable bowel syndrome (IBS), but study …

Altered functional connectivity of the amygdala in Crohn's disease

Y Fan, C Bao, Y Wei, J Wu, Y Zhao, X Zeng… - Brain Imaging and …, 2020 - Springer
Abstract Crohn's disease (CD), a chronic inflammatory bowel disease, involved in brain
structural and functional changes, including the amygdala. Amygdala is a key structure in …