Novel therapies for myocardial irritability following extreme hydroxychloroquine toxicity

PB McBeth, PI Missirlis, H Brar… - Case reports in …, 2015 - Wiley Online Library
Introduction. Hydroxychloroquine (HCQ) overdose is rare and potentially deadly when
consumed in large doses. Management of severe HCQ toxicity is limited and infrequently …

Toxicokinetics of hydroxychloroquine following a massive overdose

J de Olano, MA Howland, MK Su, RS Hoffman… - The American Journal of …, 2019 - Elsevier
Background We report a patient with a massive hydroxychloroquine overdose manifested by
profound hypokalemia and ventricular dysrhythmias and describe hydroxychloroquine …

Survival after massive hydroxychloroquine overdose

N Gunja, D Roberts, D McCoubrie… - … and intensive care, 2009 - journals.sagepub.com
Hydroxychloroquine overdose is infrequently reported and the majority of recommendations
come from the greater experience with chloroquine poisoning. We report two cases of …

Massive hydroxychloroquine overdose

S Yanturali, E Aksay, OF Demir… - Acta anaesthesiologica …, 2004 - Wiley Online Library
We report a case presenting with massive overdose of hydroxychloroquine who survived
without any sequelae. A 17‐year‐old girl presented to the Emergency Department 45 min …

Treatment of hydroxychloroquine overdose

K Marquardt, TE Albertson - The American journal of emergency medicine, 2001 - Elsevier
Hydroxychloroquine overdoses are rarely reported with 7 previous cases found in the
English medical literature. We report a case and review the literature. A 16-year-old girl …

A case of fatal hydroxychloroquine overdose

HT Fung, KK Lam, OF Wong, B Lau… - Hong Kong Journal of …, 2007 - Wiley Online Library
A 28‐year‐old woman ingested 20 g of hydroxychloroquine sulphate for suicidal attempt.
She developed hypotension, cardiac conduction disturbance, hypokalemia and …

Hydroxychloroquine overdose presenting as acquired QT interval prolongation and torsade de pointes

I Ndukwu, M Ghahramani - Journal of the American College of Cardiology, 2017 - jacc.org
Background: Hydroxychloroquine (HCQ) is an aminoquinoline derivative used as an anti-
inflammatory agent in lupus. It is a highly lipophilic substance with a large volume of …

Hydroxychloroquine overdose: toxicokinetics and management

P Jordan, JG Brookes, G Nikolic… - Journal of Toxicology …, 1999 - Taylor & Francis
Background: The management and toxicokinetics of hydroxychloroquine overdose are
poorly described. Case Report: We report a case of an 18-year-old girl who ingested 20 g of …

Acute chloroquine and hydroxychloroquine toxicity: a review for emergency clinicians

A Della Porta, K Bornstein, A Coye, T Montrief… - The American journal of …, 2020 - Elsevier
Background Acute chloroquine and hydroxychloroquine toxicity is characterized by a
combination of direct cardiovascular effects and electrolyte derangements with resultant …

Massive chloroquine intoxication: importance of early treatment and pre-hospital treatment

I Messant, N Jérémie, F Lenfant, M Freysz - Resuscitation, 2004 - Elsevier
Chloroquine intoxication, despite therapeutic improvements, remains a potentially serious
condition. We report a case of a 25-year-old patient, having ingested 10g of chloroquine, a …