Phenothiazines have been shown to inhibit the in vitro growth of multi-drug resistant
(resistant to rifampicin and isoniazid) Mycobacterium tuberculosis (MDRTB). They have …

The comparative activity of five phenothiazines against multidrug-resistant strains of
Mycobacterium tuberculosis (MDRTB) was studied using the Bactec 460 system. The order …

Increased frequency of multidrug resistant strains of Mycobacterium tuberculosis results from
inappropriate treatment and lack of patient compliance. The Center for Disease …

The in vitro and in vivo anti-mycobacterial activities of a number of phenothiazine
compounds are reviewed. These compounds, normally employed for the management of …

The phenothiazines chlorpromazine (CPZ) and thioridazine (TZ) have equal in vitro activities
against antibiotic-sensitive and-resistant Mycobacterium tuberculosis. These compounds …

Strategies to augments conventional methods of drug delivery in treatment of multiple drug
resistant tuberculosis are needed to achieve optimum results with available drugs. We have …

Objectives To investigate the effect of trimethoprim/sulfamethoxazole on the survival of
Mycobacterium tuberculosis and trimethoprim and sulfamethoxazole individually and …

The intra-and extracellular activities of 5 novel tetramethylpiperidine (TMP)-substituted
phenazines against Mycobacterium tuberculosis H37Rv (ATCC 27294) were determined …

The rise of multidrug-resistant Mycobacterium tuberculosis has complicated therapy for
tuberculosis and led us to search for a potentially active combination of drugs against these …

Chlorpromazine (CPZ) is one of several phenothiazines known to have antimicrobial
properties. It can inhibit mycobacteria, and was reported in the early literature to improve …