Prevalence, underlying causes, and preventability of sepsis-associated mortality in US acute care hospitals

C Rhee, TM Jones, Y Hamad, A Pande… - JAMA network …, 2019 - jamanetwork.com
Importance Sepsis is present in many hospitalizations that culminate in death. The
contribution of sepsis to these deaths, and the extent to which they are preventable, is …

Epidemiology of hospital-onset versus community-onset sepsis in US hospitals and association with mortality: a retrospective analysis using electronic clinical data

C Rhee, R Wang, Z Zhang, D Fram, SS Kadri… - Critical care …, 2019 - journals.lww.com
Objectives: Prior studies have reported that hospital-onset sepsis is associated with higher
mortality rates than community-onset sepsis. Most studies, however, have used inconsistent …

Current trends in sepsis-related mortality in the United States

J Prest, M Sathananthan, N Jeganathan - Critical care medicine, 2021 - journals.lww.com
OBJECTIVES: Sepsis is a life-threatening condition and is one of the leading causes of
death in the United States. The burden of sepsis-related mortality in the United States in …

Incidence and trends of sepsis in US hospitals using clinical vs claims data, 2009-2014

C Rhee, R Dantes, L Epstein, DJ Murphy, CW Seymour… - Jama, 2017 - jamanetwork.com
Importance Estimates from claims-based analyses suggest that the incidence of sepsis is
increasing and mortality rates from sepsis are decreasing. However, estimates from claims …

Assessment of health care exposures and outcomes in adult patients with sepsis and septic shock

K Fay, MRP Sapiano, R Gokhale, R Dantes… - JAMA network …, 2020 - jamanetwork.com
Importance Current information on the characteristics of patients who develop sepsis may
help in identifying opportunities to improve outcomes. Most recent studies of sepsis …

Incidence and mortality of hospital-and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis

C Fleischmann-Struzek, L Mellhammar, N Rose… - Intensive care …, 2020 - Springer
Purpose To investigate the global burden of sepsis in hospitalized adults by updating and
expanding a systematic review and meta-analysis and to compare findings with recent …

Sepsis-associated mortality, resource use, and healthcare costs: a propensity-matched cohort study

K Farrah, L McIntyre, CJ Doig, R Talarico… - Critical Care …, 2021 - journals.lww.com
Objectives: To examine long-term mortality, resource utilization, and healthcare costs in
sepsis patients compared to hospitalized nonsepsis controls. Design: Propensity-matched …

Risk factors at index hospitalization associated with longer-term mortality in adult sepsis survivors

M Shankar-Hari, DA Harrison… - JAMA network …, 2019 - jamanetwork.com
Importance Sepsis survivors, defined as adult patients who survived to hospital discharge
following a critical care unit admission for sepsis, are at increased risk of long-term mortality …

Sepsis among medicare beneficiaries: 1. The burdens of sepsis, 2012–2018

TG Buchman, SQ Simpson, KL Sciarretta… - Critical care …, 2020 - journals.lww.com
Objectives: To provide contemporary estimates of the burdens (costs and mortality)
associated with acute inpatient Medicare beneficiary admissions for sepsis. Design …

Association between state-mandated protocolized sepsis care and in-hospital mortality among adults with sepsis

JM Kahn, BS Davis, JG Yabes, CCH Chang, DH Chong… - Jama, 2019 - jamanetwork.com
Importance Beginning in 2013, New York State implemented regulations mandating that
hospitals implement evidence-based protocols for sepsis management, as well as report …