Modifiable risk factors and atrial fibrillation

DH Lau, S Nattel, JM Kalman, P Sanders - Circulation, 2017 - Am Heart Assoc
There has been increasing focus on the rising burden of atrial fibrillation (AF) since the turn
of the millennium. The AF epidemic is projected not only to have an impact on morbidity and …

[HTML][HTML] Atrial fibrillation: mechanisms, therapeutics, and future directions

J Pellman, F Sheikh - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, affecting 1% to 2% of the
general population. It is characterized by rapid and disorganized atrial activation leading to …

The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis

J Heijman, V Algalarrondo, N Voigt… - Cardiovascular …, 2016 - academic.oup.com
Atrial fibrillation (AF) is an extremely common clinical problem associated with increased
morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation …

Hypertension and atrial fibrillation: an intimate association of epidemiology, pathophysiology, and outcomes

MS Dzeshka, F Shahid, A Shantsila… - American Journal of …, 2017 - academic.oup.com
Atrial fibrillation (AF) is the most prevalent sustained arrhythmia found in clinical practice. AF
rarely exists as a single entity but rather as part of a diverse clinical spectrum of …

Atrial cardiomyopathy: pathophysiology and clinical consequences

A Goette, U Lendeckel - Cells, 2021 - mdpi.com
Around the world there are 33.5 million patients suffering from atrial fibrillation (AF) with an
annual increase of 5 million cases. Most AF patients have an established form of an atrial …

Current concepts in the pathogenesis of atrial fibrillation

A Kourliouros, I Savelieva, A Kiotsekoglou… - American heart …, 2009 - Elsevier
Current evidence suggests that the pathogenesis of atrial fibrillation (AF) is multifactorial.
The observation that AF, once present, alters the electrophysiologic properties of the atrial …

Epidemiology and natural history of atrial fibrillation: clinical implications

SS Chugh, JL Blackshear, WK Shen… - Journal of the American …, 2001 - jacc.org
With a substantial impact on morbidity and mortality, the growing “epidemic” of atrial
fibrillation (AF) intersects with a number of conditions, including aging, thromboembolism …

The bidirectional interaction between atrial fibrillation and heart failure: consequences for the management of both diseases

DVM Verhaert, HP Brunner-La Rocca… - EP …, 2021 - academic.oup.com
Atrial fibrillation (AF) and heart failure (HF) are both highly prevalent diseases and are
accompanied by a significant disease burden and increased mortality. Although the …

[HTML][HTML] Prevention and treatment of atrial fibrillation via risk factor modification

EL O'Keefe, JE Sturgess, JH O'Keefe, S Gupta… - The American journal of …, 2021 - Elsevier
Atrial fibrillation (AF) is the most common clinically significant arrhythmia, and it increases
stroke risk. A preventive approach to AF is needed because virtually all treatments such as …

Influence of inflammation and atherosclerosis in atrial fibrillation

RMFL da Silva - Current atherosclerosis reports, 2017 - Springer
Background Inflammation markers have been associated with cardiovascular diseases
including atrial fibrillation. This arrhythmia is the most frequent, with an incidence of 38/1000 …