Autophagy-induced intracellular signaling fractional nano-drug system for synergistic anti-tumor therapy

J Yan, C Shan, Z Zhang, F Li, Y Sun, Q Wang… - Journal of Colloid and …, 2023 - Elsevier
Autophagy inducers increase the sensitivity of tumor cells to chemotherapeutic drugs and
enhance anti-tumor efficacy. An autophagy-induced intracellular signaling fractional nano …

Trends in targeted delivery of nanomaterials in colon cancer diagnosis and treatment

FA Khan, R Albalawi, FH Pottoo - Medicinal research reviews, 2022 - Wiley Online Library
Colon cancer is an adenocarcinoma, which subsequently develops into malignant tumors, if
not treated properly. The current colon cancer therapy mainly revolves around …

[HTML][HTML] Hesperidin induces apoptosis and triggers autophagic markers through inhibition of Aurora-A mediated phosphoinositide-3-kinase/Akt/mammalian target of …

G Saiprasad, P Chitra, R Manikandan… - European journal of …, 2014 - Elsevier
Abnormalities in the homeostasis mechanisms involved in cell survival and apoptosis are
contributing factors for colon carcinogenesis. Interventions of these mechanisms by …

[HTML][HTML] Bisphenol A promotes the progression of colon cancer through dual-targeting of NADPH oxidase and mitochondrial electron-transport chain to produce ROS …

T Xia, J Guo, B Zhang, C Song, Q Zhao… - Frontiers in …, 2022 - frontiersin.org
Bisphenol A (BPA) is a high-production-volume industrial chemical. Despite recent research
conducted on its carcinogenicity, its role in the development of colon cancer (CC) has been …

Inhibition of tumor progression by oral piceatannol in mouse 4T1 mammary cancer is associated with decreased angiogenesis and macrophage infiltration

H Song, JI Jung, HJ Cho, S Her, SH Kwon, R Yu… - The Journal of nutritional …, 2015 - Elsevier
Piceatannol, a polyphenol which exhibits anticancer activities, is found in grapes, red wine
and berries. It has been shown to inhibit several transcription factor pathways. The present …

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM

JS Woo, GS Choo, ES Yoo… - Molecular …, 2020 - spandidos-publications.com
Apigenin, an aromatic compound, exhibits antioxidant, anti-inflammatory and anti-viral
effects. The present study aimed to investigate the effects of apigenin on cell proliferation …

Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K …

L Zhang, C Chen, J Duanmu, Y Wu, J Tao… - International …, 2018 - Elsevier
The aim of this study was to evaluate the pharmacological effects of CPT on CT26 colon
cancer cells in vivo and in vitro, and to reveal the potential mechanism. CPT suppressed the …

Efficacy of PLGA-loaded apigenin nanoparticles in Benzo [a] pyrene and ultraviolet-B induced skin cancer of mice: Mitochondria mediated apoptotic signalling …

S Das, J Das, A Samadder, A Paul… - Food and chemical …, 2013 - Elsevier
Skin cancer is increasing at an alarming rate and becoming resistant to conventional
chemotherapy necessitating improved drug delivery system. We loaded apigenin (Ap), a …

Selective anticancer therapy using pro-oxidant drug-loaded chitosan–fucoidan nanoparticles

DG Choi, J Venkatesan, MS Shim - International Journal of Molecular …, 2019 - mdpi.com
Pro-oxidant therapy exploiting pro-oxidant drugs that can trigger cytotoxic oxidative stress in
cancer cells has emerged as an innovative strategy for cancer-specific therapy …

The inhibitory effect of hesperidin on tumor cell invasiveness occurs via suppression of activator protein 1 and nuclear factor-kappaB in human hepatocellular …

KH Lee, MH Yeh, ST Kao, CM Hung, CJ Liu, YY Huang… - Toxicology letters, 2010 - Elsevier
Hesperidin (HES) has been reported to exhibit anti-invasive and antimetastatic activities by
suppressing the enzymatic activity of matrix metalloproteinase-9 (MMP-9). However, the …