[HTML][HTML] MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff

R Yu, T Liu, SB Jin, C Ning, U Lendahl, M Nistér… - Scientific reports, 2017 - nature.com
Mitochondrial dynamics is a fundamental cellular process and recruitment of Drp1 to
mitochondria is an essential step in mitochondrial fission. Mff and MIEF1/2 (MiD51/49) serve …

The Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes

C Sugden, MD Urbaniak, T Araki… - Molecular Biology of the …, 2015 - Am Soc Cell Biol
Differentiation-inducing factor-1 (DIF-1) is a polyketide that induces Dictyostelium amoebae
to differentiate as prestalk cells. We performed a global quantitative screen for …

DIF-1, an anti-tumor substance found in Dictyostelium discoideum, inhibits progesterone-induced oocyte maturation in Xenopus laevis

Y Kubohara, Y Hanaoka, E Akaishi… - European journal of …, 2003 - Elsevier
Differentiation-inducing factor-1 (DIF-1; 1-(3, 5-dichloro-2, 6-dihydroxy-4-methoxyphenyl)
hexan-1-one) is a putative morphogen that induces stalk-cell formation in the cellular slime …

Dictyostelium differentiation‐inducing factor‐1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells

W Omata, H Shibata, M Nagasawa, I Kojima… - The FEBS …, 2007 - Wiley Online Library
The differentiation‐inducing factor‐1 (DIF‐1) is a signal molecule that induces stalk cell
formation in the cellular slime mold Dictyostelium discoideum, while DIF‐1 and its analogs …

[PDF][PDF] Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42

J Peng, BJ Wallar, A Flanders, PJ Swiatek, AS Alberts - Current Biology, 2003 - cell.com
Abstract Background: Mammalian Diaphanous-related formins (Drfs) act as Rho small
GTPase effectors during growth factor-induced cytoskeletal remodeling and cell division …

[HTML][HTML] Mitochondrial translocation of cofilin is required for allyl isothiocyanate-mediated cell death via ROCK1/PTEN/PI3K signaling pathway

G Li, Q Cheng, L Liu, T Zhou, C Shan, X Hu… - Cell communication and …, 2013 - Springer
Background Cofilin is a member of the actin depolymerizing factor (ADF)/cofilin family, which
regulates actin dynamics. Increasing evidence suggests that mitochondrial translocation of …

Cofilin‐2, a novel type of cofilin, is expressed specifically at aggregation stage of Dictyostelium discoideum development

H Aizawa, Y Kishi, K Iida, M Sameshima… - Genes to Cells, 2001 - Wiley Online Library
Background A conventional cofilin, cofilin‐1 in Dictyostelium discoideum plays significant
roles in cell proliferation, phagocytosis, chemotactic movement and macropinocytosis …

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

OC Losón, Z Song, H Chen… - Molecular biology of the …, 2013 - Am Soc Cell Biol
Several mitochondrial outer membrane proteins—mitochondrial fission protein 1 (Fis1),
mitochondrial fission factor (Mff), mitochondrial dynamics proteins of 49 and 51 kDa (MiD49 …

Differentiation-inducing factor-1-induced growth arrest of K562 leukemia cells involves the reduction of ERK1/2 activity

E Akaishi, T Narita, S Kawai, Y Miwa, T Sasaguri… - European journal of …, 2004 - Elsevier
The differentiation-inducing factor-1 (DIF-1) is a signal molecule that induces stalk cell
differentiation in the cellular slime mold Dictyostelium discoideum. In addition, DIF-1 is a …

Differentiation-inducing factor-1 prevents hepatic stellate cell activation through inhibiting GSK3β inactivation

S Furukawa, M Yamaguchi, A Ooka, H Kikuchi… - Biochemical and …, 2019 - Elsevier
Abstract Differentiation-inducing factor-1 (DIF-1), a morphogen produced by the cellular
slime mold Dictyostelium discoideum, is a natural product that has attracted considerable …