Noradrenergic regulation of cue-guided decision making and impulsivity is doubly dissociable across frontal brain regions

CS Chernoff, TJ Hynes, JD Schumacher… - …, 2024 - Springer
Rationale Win-paired stimuli can promote risk taking in experimental gambling paradigms in
both rats and humans. We previously demonstrated that atomoxetine, a noradrenaline …

Effects of nicotine exposure and anxiety on motivation for reward and gambling-like cues under reward uncertainty.

TI Russell, MJF Robinson - Behavioral neuroscience, 2019 - psycnet.apa.org
Reward uncertainty is a common characteristic of gambling and may powerfully enhance
attraction to gambling-related cues, thus promoting maladaptive gambling behaviors in …

Decision-making in gambling disorder: understanding behavioral addictions

L Clark - Decision Neuroscience, 2017 - Elsevier
Examples from real-world gambling behavior have been a frequent source of inspiration to
the fields of behavioral economics and decision neuroscience, but it is surprising how little is …

Cue-elicited reward-seeking requires extracellular signal-regulated kinase activation in the nucleus accumbens

MW Shiflett, RP Martini, JC Mauna… - Journal of …, 2008 - Soc Neuroscience
The motivation to seek out rewards can come under the control of stimuli associated with
reward delivery. The ability of cues to motivate reward-seeking behavior depends on the …

Ethanol exposure history and alcoholic reward differentially alter dopamine release in the nucleus accumbens to a reward‐predictive cue

AM Fiorenza, TA Shnitko, KM Sullivan… - Alcoholism: Clinical …, 2018 - Wiley Online Library
Background Conditioned stimuli (CS) that predict reward delivery acquire the ability to
induce phasic dopamine release in the nucleus accumbens (NAc). This dopamine release …

Reward sensitivity, decisional bias, and metacognitive deficits in cocaine drug addiction

M Balconi, R Finocchiaro… - Journal of addiction …, 2014 - journals.lww.com
Objectives: The present research explored the effect of reward sensitivity bias and
metacognitive deficits on substance use disorder (SUD) in the decision-making process …

Opioid reward 'liking'and 'wanting'in the nucleus accumbens

S Peciña - Physiology & behavior, 2008 - Elsevier
Whether we 'like'and 'want'stimuli depends partially on opioid neurotransmission within the
nucleus accumbens. But how are 'liking'and 'wanting'organized within this neural substrate …

Sign tracking predicts suboptimal behavior in a rodent gambling task

M Swintosky, JT Brennan, C Koziel, JP Paulus… - …, 2021 - Springer
Rationale Reward-associated cues can promote maladaptive behavior, including risky
decision-making in a gambling setting. A propensity for sign tracking over goal tracking—ie …

[HTML][HTML] A closer look at the effects of repeated cocaine exposure on adaptive decision-making under conditions that promote goal-directed control

B Halbout, AT Liu, SB Ostlund - Frontiers in psychiatry, 2016 - frontiersin.org
It has been proposed that compulsive drug seeking reflects an underlying dysregulation in
adaptive behavior that favors habitual (automatic and inflexible) over goal-directed …

What is abnormal about addiction-related attentional biases?

BA Anderson - Drug and alcohol dependence, 2016 - Elsevier
Background The phenotype of addiction includes prominent attentional biases for drug cues,
which play a role in motivating drug-seeking behavior and contribute to relapse. In a …