The hepatic immune system can induce rapid and controlled responses to pathogenic
microorganisms and tumor cells. Accordingly, most of the microorganisms that reach the …

BACKGROUND & AIMS: Hepatic involvement is frequent in human brucellosis. While
different histopathological lesions have been reported in these patients, the underlying …

The liver is frequently affected in patients with active brucellosis. The present study
demonstrates that Brucella abortus infection induces the activation of the autophagic …

In patients with active brucellosis, the liver is frequently affected by histopathologic lesions,
such as granulomas, inflammatory infiltrations, and parenchymal necrosis. Herein, we …

In human brucellosis, the liver is frequently affected. Brucella abortus triggers a profibrotic
response on hepatic stellate cells (HSCs) characterized by inhibition of MMP-9 with …

Bacteria of the genus Brucella are Gram-negative pathogens of several animal species that
cause a zoonotic disease in humans known as brucellosis or Malta fever. Within their hosts …

Brucella can parasitize within human antigen-presenting cells modifying phagocytosis,
phagolysosome fusion, antigen presentation, cytokine secretion, and apoptosis. Subversion …

In humans, pathogenic Brucella species cause a febrile illness known as brucellosis. A key
pathogenic trait of this group of organisms is their ability to survive in immune cells and …

Brucella spp. are intracellular bacterial pathogens that cause infection in domestic and wild
animals. They are often used as model organisms to study intracellular bacterial infections …

In Brucellosis, the role of hepatic stellate cells (HSCs) in the induction of liver fibrosis has
been elucidated recently. Here, we study how the infection modulates the antigen …