Stimulation of the inflammatory reflex (IR) is a promising strategy to treat systemic
inflammatory disorders. However, this strategy is hindered by the cost and side effects of …

Stimulation of the inflammatory reflex (IR) is a promising strategy for treating systemic
inflammatory disorders. Recent studies suggest oral sodium bicarbonate (NaHCO3) as a …

The cholinergic anti-inflammatory pathway is the efferent arm of the inflammatory reflex, a
neural circuit through which the CNS can modulate peripheral immune responses. Signals …

Much research now indicates that vagal nerve stimulation results in a systemic reduction in
inflammatory cytokine production and an increase in anti-inflammatory cell populations that …

In COPD, the activity of the cholinergic system is increased, which is one of the reasons for
the airflow limitation caused by the contraction of airway smooth muscles. Therefore …

C1 neurons, located in the medulla oblongata, mediate adaptive autonomic responses to
physical stressors (for example, hypotension, hemorrhage and presence of …

New findings on neural regulation of immunity are allowing the design of novel
pharmacological strategies to control inflammation and nociception. Herein, we report that …

Macrophage cytokine production is regulated by neural signals, for example in the
inflammatory reflex. Signals in the vagus and splenic nerves are relayed by choline …

We tested the hypothesis that oral NaHCO 3 intake stimulates splenic anti-inflammatory
pathways. Following oral NaHCO 3 loading, macrophage polarization was shifted from …

On 7–8 September 2012, at Bolton Landing, New York, the International Association of
Inflammation Societies (IAIS) hosted a Translational Inflammation Summit which gathered a …