Lower HIV-2 plasma viral loads may explain differences between the natural histories of HIV-1 and HIV-2 infections

V Shanmugam, WM Switzer… - JAIDS Journal of …, 2000 - journals.lww.com
To explain the low transmissibility and pathogenicity of HIV-2 infection's plasma viral loads
in both HIV-1-and HIV-2-infected persons were compared by using the polymerase chain …

The influence of lymphocyte counts and disease progression on circulating and inducible anti-HIV-1 cytotoxic T-cell activity in HIV-1-infected subjects

MD Grant, FM Smaill, DP Singal, KL Rosenthal - Aids, 1992 - journals.lww.com
Objective: To evaluate specific anti-HIV cytotoxic T-lymphocyte (CTL) activity in relation to
basic clinical and laboratory parameters used to follow HIV infection. Methods: Lymphocytes …

Transmission of HTLV-I and HIV among homosexual men in Trinidad

C Bartholomew, WC Saxinger, JW Clark, M Gail… - Jama, 1987 - jamanetwork.com
Risk for human T-cell lymphotropic virus type I (HTLV-I) and human immunodeficiency virus
(HIV) infection was evaluated in 100 homosexual or bisexual men from Trinidad. High …

Correlates of protection in HIV infection and the progression of HIV infection to AIDS

M Clerici, GM Shearer - Immunology letters, 1996 - Elsevier
Exposure to human immunodeficency virus (HIV) can result in HIV infection which is defined
by seroconversion and the detection of HIV-specific antibodies. Nevertheless, in every …

The clinical significance of HTLV-I and HTLV-II infection in the AIDS epidemic.

LT Pierik, EL Murphy - AIDS clinical review, 1991 - europepmc.org
Although early reports of an etiological role of HTLV-I in AIDS are not supported by
subsequent epidemiologic and biologic data, all AIDS specialists should be aware of the …

Impact of early HIV-1 RNA and T-lymphocyte dynamics during primary HIV-1 infection on the subsequent course of HIV-1 RNA levels and CD4+ T-lymphocyte counts …

GR Kaufmann, P Cunningham… - JAIDS Journal of …, 1999 - journals.lww.com
Plasma HIV-1 RNA and CD4+ T-cell counts after HIV-1 seroconversion are important
independent markers that predict the clinical course of HIV-1 infection. The prognostic …

Anti-HIV type 1 cytotoxic T lymphocyte effector activity and disease progression in the first 8 years of HIV type 1 infection of homosexual men

CR RINALDO JR, LA BELTZ, XLI HUANG… - AIDS research and …, 1995 - liebertpub.com
Cytotoxic T lymphocytes (CTL) may play an important role in host defense against HIV-1
infection. In this study, we examined the responses of circulating effector CTL (CTLe) …

Within-subject variation in CD4 lymphocyte count in asymptomatic human immunodeficiency virus infection: implications for patient monitoring

MD Hughes, DS Stein, HM Gundacker… - Journal of Infectious …, 1994 - academic.oup.com
Abstract Changes in CD4 lymphocyte counts are widely used in monitoring human
immunodeficiency virus (HIV)-infected patients for disease progression. However, random …

Correlation between plasma HIV-1 RNA levels and the rate of immunologic decline

R Iuliano, G Forastieri, M Brizzi, L Mecocci… - JAIDS Journal of …, 1997 - journals.lww.com
To determine the influence of HIV-1 replication on immunologic decline and clinical
outcome, we quantified the HIV-1 plasma viral load in 20 patients at different times over a …

Equal Plasma Viral Loads Predict a Similar Rate of CD4± T Cell Decline in Human Immunodeficiency Virus (HIV) Type 1- and HIV-2-Infected Individuals from …

GS Gottlieb, PS Sow, SE Hawes, I Ndoye… - The Journal of …, 2002 - academic.oup.com
Human immunodeficiency virus (HIV) type 2 infection is characterized by slower disease
progression to acquired immunodeficiency syndrome than results from HIV-1 infection. To …