Vitamin D deficiency induces the excitation/inhibition brain imbalance and the proinflammatory shift

LA Kasatkina, AS Tarasenko, OO Krupko… - … International Journal of …, 2020 - Elsevier
Vitamin D 3 is among the major neurosteroids whose role in developing and adult brain is
intensively studied now. Its active form 1, 25 (OH) 2 D 3 regulates the expression and …

Vitamin D as a neurosteroid affecting the developing and adult brain

NJ Groves, JJ McGrath, THJ Burne - Annual review of nutrition, 2014 - annualreviews.org
Vitamin D deficiency is prevalent throughout the world, and growing evidence supports a
requirement for optimal vitamin D levels for the healthy developing and adult brain. Vitamin …

The effects of vitamin D on brain development and adult brain function

JP Kesby, DW Eyles, THJ Burne, JJ McGrath - Molecular and cellular …, 2011 - Elsevier
A role for vitamin D in brain development and function has been gaining support over the
last decade. Multiple lines of evidence suggest that this vitamin is actually a neuroactive …

[HTML][HTML] Vitamin D and the central nervous system: Causative and preventative mechanisms in brain disorders

X Cui, DW Eyles - Nutrients, 2022 - mdpi.com
Twenty of the last one hundred years of vitamin D research have involved investigations of
the brain as a target organ for this hormone. Our group was one of the first to investigate …

[HTML][HTML] Role of vitamin D in cognitive dysfunction: new molecular concepts and discrepancies between animal and human findings

Z Gáll, O Székely - Nutrients, 2021 - mdpi.com
Purpose of review: increasing evidence suggests that besides the several metabolic,
endocrine, and immune functions of 1alpha, 25-dihydroxyvitamin D (1, 25 (OH) 2D), the …

The vitamin D neuroendocrine system as a target for novel neurotropic drugs

AV Kalueff, A Minasyan, T Keisala… - CNS & Neurological …, 2006 - ingentaconnect.com
Vitamin D is a seco-steroid hormone with multiple functions in the nervous system.
Physiological brain mechanisms of vitamin D and its receptors include neuroprotection …

Vitamin D: Brain and behavior

DW Eyles - Journal of Bone and Mineral Research Plus, 2021 - academic.oup.com
It has been 20 years since we first proposed vitamin D as a “possible” neurosteroid.(1) Our
work over the last two decades, particularly results from our cellular and animal models, has …

Vitamin D and the brain: Genomic and non-genomic actions

X Cui, H Gooch, A Petty, JJ McGrath, D Eyles - Molecular and cellular …, 2017 - Elsevier
Abstract 1, 25 (OH) 2 D 3 (vitamin D) is well-recognized as a neurosteroid that modulates
multiple brain functions. A growing body of evidence indicates that vitamin D plays a pivotal …

Vitamin D and the brain

LR Harms, THJ Burne, DW Eyles, JJ McGrath - Best practice & research …, 2011 - Elsevier
Vitamin D is a member of the superfamily of nuclear steroid transcription regulators and as
such, exerts transcriptional control over a large number of genes. Several other steroids …

The Synaptic and Circuit Functions of Vitamin D in Neurodevelopment Disorders

X Ye, Q Zhou, P Ren, W Xiang… - … Disease and Treatment, 2023 - Taylor & Francis
Vitamin D deficiency/insufficiency is a public health issue around the world. According to
epidemiological studies, low vitamin D levels have been associated with an increased risk of …