An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

U Dube, JL Del-Aguila, Z Li, JP Budde, S Jiang… - Nature …, 2019 - nature.com
Parietal cortex RNA-sequencing (RNA-seq) data were generated from individuals with and
without Alzheimer disease (AD; n control= 13; n AD= 83) from the Knight Alzheimer Disease …

The emerging role of circular RNAs in Alzheimer's disease and Parkinson's disease

M Zhang, Z Bian - Frontiers in aging neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) and Parkinson's disease (PD) are two neurodegenerative
diseases (NDDs) commonly found in elderly patients that are difficult to diagnose and lack …

Circular RNA (circRNA) in Alzheimer's disease (AD)

WJ Lukiw - Frontiers in genetics, 2013 - frontiersin.org
Circular RNAs (circRNAs) are a naturally occurring family of noncoding RNAs (ncRNAs)
highly represented in the eukaryotic transcriptome. Recently characterized, traditional …

Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease

X Dong, Y Bai, Z Liao, D Gritsch, X Liu, T Wang… - Nature …, 2023 - nature.com
Little is known about circular RNAs (circRNAs) in specific brain cells and human
neuropsychiatric disease. Here, we systematically identify over 11,039 circRNAs expressed …

Annotation and functional clustering of circRNA expression in rhesus macaque brain during aging

K Xu, D Chen, Z Wang, J Ma, J Zhou, N Chen, L Lv… - Cell discovery, 2018 - nature.com
The abundance and function of circular RNAs (circRNAs) in mammalian brain have been
reported, but their alterations in the biology of brain aging remain elusive. Here, using deep …

Exploring the regulatory role of circular RNAs in neurodegenerative disorders

E D'Ambra, D Capauto, M Morlando - International journal of molecular …, 2019 - mdpi.com
Circular RNAs (circRNAs) are a distinctive class of regulatory non-coding RNAs
characterised by the presence of covalently closed ends. They are evolutionary conserved …

[HTML][HTML] The landscape of circular RNA expression in the human brain

A Gokool, F Anwar, I Voineagu - Biological psychiatry, 2020 - Elsevier
Abstract Background Circular RNAs (circRNAs) are enriched in the mammalian brain and
upregulated in response to neuronal differentiation and depolarization. These RNA …

[HTML][HTML] Circular RNA expression and function in the brain

S Sekar, WS Liang - Non-coding RNA research, 2019 - Elsevier
Within the last decade, active research on circular RNAs (circRNAs) has dramatically
improved our understanding of the expression and function of these non-coding RNAs …

Regulatory role of circular RNAs and neurological disorders

G Floris, L Zhang, P Follesa, T Sun - Molecular neurobiology, 2017 - Springer
Circular RNAs (circRNAs) are a class of long noncoding RNAs that are characterized by the
presence of covalently linked ends and have been found in all life kingdoms. Exciting …

[HTML][HTML] Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed

A Rybak-Wolf, C Stottmeister, P Glažar, M Jens, N Pino… - Molecular cell, 2015 - cell.com
Circular RNAs (circRNAs) are an endogenous class of animal RNAs. Despite their
abundance, their function and expression in the nervous system are unknown. Therefore …