Healthy immune function depends on precise regulation of lymphocyte activation. During the
National Aeronautics and Space Administration (NASA) Apollo and Shuttle eras, multiple …

As spaceflight becomes more common with commercial crews, blood-based measures of
crew health can guide both astronaut biomedicine and countermeasures. By profiling …

Spaceflight induces an immune response in astronauts. To better characterize this effect, we
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …

Human exposure to microgravity is considered the major environmental factor of space flight
that affects cells and tissues causing adverse effects to human health. Ground based gravity …

Microgravity impacts various aspects of human health. Yet the mechanisms of spaceflight-
induced health problems are not elucidated. Here, we mapped the fusion systemic analysis …

During spaceflights, astronauts face different forms of stress (eg, socio-environmental and
gravity stresses) that impact physiological functions and particularly the immune system. In …

Exposure to microgravity during space flight (SF) of variable length induces suffering of the
endothelium (the cells lining all blood vessels), mostly responsible for health problems …

Despite the development and great progress in the field of space biology, the astronauts are
still facing many challenges in space. The space environment in which astronauts stay …

Increased oxidative stress is an unavoidable consequence of exposure to the space
environment. Our previous studies showed that mice exposed to space for 13.5 days had …

Spaceflight entails various stressful environmental factors including microgravity. The effects
of gravity changes have been studied extensively on skeletal, muscular, cardiovascular …