Cerebrospinal fluid concentrations of nimodipine correlate with long-term outcome in aneurysmal subarachnoid hemorrhage: pilot study

R Riva, M Pegoli, M Contin, A Perrone… - Clinical …, 2019 - journals.lww.com
Objectives The aim was to evaluate plasma and cerebrospinal fluid (CSF) nimodipine
concentrations in patients with aneurysmal subarachnoid hemorrhage and their correlation …

Serum levels of nimodipine in enteral and parenteral administration in patients with aneurysmal subarachnoid hemorrhage

T Abboud, H Andresen, J Koeppen, P Czorlich… - Acta …, 2015 - Springer
Background The aim of this study was to evaluate serum nimodipine concentrations in
patients with aneurysmal subarachnoid hemorrhage (SAH) after parenteral therapy and a …

Nimodipine dose reductions in the treatment of patients with aneurysmal subarachnoid hemorrhage

N Sandow, D Diesing, A Sarrafzadeh, P Vajkoczy… - Neurocritical Care, 2016 - Springer
Background The incidence of cerebral infarction and poor outcome in patients with
aneurysmal subarachnoid hemorrhage (aSAH) is reduced by oral nimodipine but acute …

Early-phase pharmacokinetics of enteral and parenteral nimodipine in patients with acute subarachnoid haemorrhage–a pilot study

V Soppi, H Kokki, T Koivisto, M Lehtonen… - European journal of …, 2007 - Springer
Objective The pharmacokinetics of nimodipine following enteral administration in the early
phase after subarachnoid haemorrhage (SAH) has not been described. If a sufficient …

Nimodipine in aneurysmal subarachnoid hemorrhage: a randomized study of intravenous or peroral administration

E Kronvall, P Undrén, B Romner, H Säveland… - Journal of …, 2009 - thejns.org
Object The calcium antagonist nimodipine has been shown to reduce the incidence of
ischemic complications following aneurysmal subarachnoid hemorrhage (SAH). Although …

[HTML][HTML] Nimodipine pharmacokinetic variability in various patient populations

SH Mahmoud, X Ji, FA Isse - Drugs in R&D, 2020 - Springer
Nimodipine has been shown to improve outcomes following aneurysmal subarachnoid
hemorrhage. Guidelines recommend that all patients receive a fixed dose of oral nimodipine …

Acute effects of nimodipine on cerebral vasculature and brain metabolism in high grade subarachnoid hemorrhage patients

HA Choi, SB Ko, H Chen, E Gilmore, AM Carpenter… - Neurocritical Care, 2012 - Springer
Background Nimodipine is the only medication shown to improve outcomes after
aneurysmal subarachnoid hemorrhage (SAH). Preliminary theories regarding the …

Nimodipine pharmacokinetics after intraventricular injection of sustained-release nimodipine for subarachnoid hemorrhage

RL Macdonald, D Hänggi, P Strange, HJ Steiger… - Journal of …, 2019 - thejns.org
OBJECTIVE The objective of this study was to measure the concentration of nimodipine in
CSF and plasma after intraventricular injection of a sustained-release formulation of …

[HTML][HTML] Nimodipine systemic exposure and outcomes following aneurysmal subarachnoid hemorrhage: a pilot prospective observational study (ASH-1 study)

SH Mahmoud, F Hefny, FA Isse, S Farooq… - Frontiers in …, 2024 - frontiersin.org
Background Nimodipine improves outcomes following aneurysmal subarachnoid
hemorrhage (aSAH). Guidelines recommend that all patients should receive a fixed-dose …

Incidence of arterial hypotension in patients receiving peroral or continuous intra-arterial nimodipine after aneurysmal or perimesencephalic subarachnoid …

M Kieninger, M Gruber, I Knott, K Dettmer, PJ Oefner… - Neurocritical care, 2019 - Springer
Background Oral nimodipine is used for prophylaxis and treatment of delayed cerebral
ischemia in patients with aneurysmal or perimesencephalic subarachnoid hemorrhage …