Abstract Information processing in neocortical circuits requires integrating inputs over a wide
range of spatial scales, from local microcircuits to long-range cortical and subcortical …

The local and long-range connectivity of cortical neurons are considered instrumental to the
functional repertoire of the cortical region in which they reside. In cortical networks, distinct …

The medial prefrontal cortex (mPFC) contains populations of GABAergic interneurons that
play different roles in cognition and emotion. Their local and long-range inputs are …

Long-range projections from the frontal cortex are known to modulate sensory processing in
multiple modalities. Although the mouse has become an increasingly important animal …

A recombinant rabies virus was used as a retrograde tracer to allow complete fi lling of the
axonal and dendritic arbors of identifi ed projection neurons in layer 5 of mouse primary …

The dorsal striatum integrates inputs from multiple brain areas to coordinate voluntary
movements, associative plasticity, and reinforcement learning. Its projection neurons consist …

Basal ganglia and the cerebellum are part of a densely interconnected network. While both
subcortical structures process information in basically segregated loops that primarily …

Identification of structural connections between neurons is a prerequisite to understanding
brain function. Here we developed a pipeline to systematically map brain-wide …

We have used retrograde transneuronal transport of rabies virus to examine basal ganglia
connections with the cerebral cortex. We injected rabies into the primary motor cortex (M1) …

Deciphering how neural circuits are anatomically organized with regard to input and output
is instrumental in understanding how the brain processes information. For example, locus …