p6e monoclonal antibody HNK-1 reacts exclusively with human granular lymphocytes that
comprise 16+/-1.4% of blood mononuclear cells. In normal individuals, almost all natural …

Background: Natural killer (NK) cells are crucial components of the innate immune system
that fight tumors and viral infections. Patients with colorectal cancer (CRC) have a poor …

Natural Killer (NK) cells are effector lymphocytes involved in tumor immunosurveillance,
however, the specific mechanism in hepatocellular carcinoma (HCC) has not been well …

The mechanisms linking hepatitis B virus (HBV) and hepatitis C virus (HCV) infection to
hepatocellular carcinoma (HCC) remain largely unknown. Natural killer (NK) cells account …

Background Immunotherapy with immune checkpoint inhibitors for non-small cell lung
cancer (NSCLC) has emerged as an important treatment option. Although immunotherapy …

In recent years, circulating tumor cells (CTCs) in metastatic cancer patients have been found
to be a promising biomarker to predict overall survival and tumor progression in these …

Functional defects in natural killer (NK) cells have been proposed to be responsible for the
failure of anti-tumor immune responses. Whether and how NK cells are impaired in …

The efficacy of tumor cell–immune cell interactions depends on a number of factors, for
example, the expression of HLA-I on tumor cells, the type of immune cell, the accessibility of …

Background This randomized clinical study was conducted to evaluate the therapeutic
benefits of cytokine-induced killer (CIK) cell immunotherapy in combination with …

Natural killer (NK) cells are innate effector lymphocytes widely involved in cancer
immunosurveillance. In this study, we described three circulating NK cell subsets in patients …