[PDF][PDF] Interactions between aspirin and P2Y12 receptor antagonists in ischaemic heart disease

W Parker - 2020 - etheses.whiterose.ac.uk
A combination of aspirin 75 mg once daily (OD) and the P2Y12 inhibitor ticagrelor
represents the current standard antiplatelet treatment for acute coronary syndromes (ACS) …

Novel approaches to P2Y12 inhibition and aspirin dosing

WAE Parker, RF Storey - Platelets, 2021 - Taylor & Francis
Aspirin and P2Y12 inhibitors remain commonly prescribed antiplatelet drugs in the treatment
of atherothrombotic conditions. Despite established benefits of dual antiplatelet therapy …

Impact of Aspirin Dosing on the Effects of P2Y12 Inhibition in Patients with Acute Coronary Syndromes

MR Thomas, RF Storey - Journal of cardiovascular translational research, 2014 - Springer
The discovery of the antiplatelet effect of low-dose aspirin led to the hugely successful
strategy of dual antiplatelet therapy in patients with acute coronary syndromes (ACS) …

[HTML][HTML] Moving Toward Ticagrelor Monotherapy: Like Boats Against the Current

G Sharma, DI Feldman, JA Bittl - Cardiovascular Interventions, 2021 - jacc.org
Aspirin has been the cornerstone of antithrombotic therapy for the treatment of acute
coronary syndromes (ACS) for more than 3 decades (1), and along with a P2Y12 inhibitor …

The long journey of individualizing antiplatelet therapy after acute coronary syndromes

RF Storey - European Heart Journal, 2020 - academic.oup.com
Acute coronary syndromes (ACS) are most commonly, but not exclusively, precipitated by
atherosclerotic plaque rupture or erosion, leading to a platelet-driven thrombotic response …

[HTML][HTML] Aspirin withdrawal in patients treated with ticagrelor presenting with non‐ST elevation myocardial infarction

R Beigel, I Mazin, E Koifman, M Shechter… - Journal of Thrombosis …, 2018 - Elsevier
Essentials• Strong P2Y 12 blockade may cause platelet inhibition that is only minimally
enhanced by aspirin.• We evaluated aspirin withdrawal on platelet reactivity in ticagrelor …

Benefit and risks of aspirin in addition to ticagrelor in acute coronary syndromes: a post hoc analysis of the randomized GLOBAL LEADERS trial

M Tomaniak, P Chichareon, Y Onuma… - JAMA …, 2019 - jamanetwork.com
Importance The role of aspirin as part of antiplatelet regimens in acute coronary syndromes
(ACS) needs to be clarified in the context of newer potent P2Y12 antagonists. Objective To …

Current controversies in the use of aspirin and ticagrelor for the treatment of thrombotic events

A Myat, US Tantry, J Kubica… - Expert review of …, 2016 - Taylor & Francis
ABSTRACT Introduction: A P2Y12 inhibitor plus aspirin is the most widely used antiplatelet
strategy to prevent adverse outcomes in the setting of atherothrombotic vascular disease …

Rapid desensitization of the patients with aspirin hypersensitivity and coronary artery disease

US Tantry, PA Gurbel - Circulation: Cardiovascular Interventions, 2017 - Am Heart Assoc
2 Tantry and Gurbel Aspirin Desensitization completed the desensitization protocol were
discharged on 100-mg aspirin per day, and 69.4% were on dual antiplatelet therapy. The …

[HTML][HTML] Prasugrel or Ticagrelor for Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Does it Matter?

J Giri, A Nathan - JACC: Cardiovascular Interventions, 2018 - jacc.org
The addition of P2Y12 receptor inhibitors to aspirin therapy has substantially improved the
care of patients with acute coronary syndromes (ACS) and those undergoing percutaneous …