Background: The objective of this narrative review of local anesthetic systemic toxicity is to
provide an update on its prevention, diagnosis, and management. Methods: The authors …

This review summarizes presenting features, management, and outcomes of local
anesthetic systemic toxicity (LAST) from published cases and those submitted to online …

The accidental overdose of local anesthetics may prove fatal. The commonly used amide
local anesthetics have varying adverse effects on the myocardium, and beyond a certain …

Local anesthetic systemic toxicity (LAST) occurrence may cross several medical specialties.
In 2010, the American Society of Regional Anesthesia and Pain Medicine (ASRA) published …

Well-placed local anaesthetics (LAs) can yield great clinical benefits. But systemic toxicity
related to their use can be devastating. The highly publicized case in 2004 of Mayra …

Local anesthetic systemic toxicity (LAST) is a rare yet devastating complication from the
administration of local anesthesia. The ability to recognize and treat LAST is critical for …

Background: Following national and regional recommendations, intravenous lipid emulsion
(ILE) has become established in clinical practice as a treatment for acute local anesthetic …

Cardiovascular collapse from accidental local anesthetic toxicity is a rare but catastrophic
complication of regional anesthesia. The long-acting amide local anesthetics bupivacaine …

Local anesthetic systemic toxicity (LAST) is a life-threatening adverse event that may occur
after the administration of local anesthetic drugs through a variety of routes. Increasing use …

Background: Lipid infusion reverses systemic local anesthetic toxicity. The acceptable upper
limit for lipid administration is unknown and has direct bearing on clinical management. We …