Background An advantageous but challenging approach to overcome the limited supply of
petroleum and relieve the greenhouse effect is to produce bulk chemicals from renewable …

As the importance of reducing carbon emissions as a means to limit the serious effects of
global climate change becomes apparent, synthetic biologists and metabolic engineers are …

Fatty alcohols are important components of a vast array of surfactants, lubricants, detergents,
pharmaceuticals and cosmetics. We have engineered Saccharomyces cerevisiae to …

Robust microorganisms are necessary for economical bioethanol production. However,
such organisms must be able to effectively ferment both hexose and pentose sugars present …

Fatty acid-derived biofuels can be a better solution than bioethanol to replace petroleum
fuel, since they have similar energy content and combustion properties as current …

Saccharomyces cerevisiae has been engineered for producing ethanol from xylose, the
second most abundant sugar in cellulosic biomass hydrolyzates. Heterologous expressions …

Bioconversion of xylose—the second most abundant sugar in nature—into high‐value fuels
and chemicals by engineered Saccharomyces cerevisiae has been a long‐term goal of the …

Sugar alcohols find applications in pharmaceuticals, oral and personal care products, and
as intermediates in chemical synthesis. While industrial-scale production of these …

Background Fermentation of xylose to ethanol has been achieved in S. cerevisiae by
genetic engineering. Xylose utilization is however slow compared to glucose, and during …

Fatty aldehydes and alcohols are valuable precursors used in the industrial manufacturing
of a myriad of specialty products. Herein, we demonstrate the de novo production of odd …