Nanoparticle-mediated delivery of siRNA for effective lung cancer therapy
YD Kim, TE Park, B Singh, S Maharjan, YJ Choi… - …, 2015 - Future Medicine
Lung cancer is one of the most lethal diseases worldwide, and the survival rate is less than
15% even after the treatment. Unfortunately, chemotherapeutic treatments for lung cancer …
15% even after the treatment. Unfortunately, chemotherapeutic treatments for lung cancer …
The importance of co‐delivery of nanoparticle‐siRNA and anticancer agents in cancer therapy
N Khelghati… - Chemical Biology & …, 2021 - Wiley Online Library
According to global statistics, cancer is the second leading cause of death worldwide.
Because of the heterogeneity of cancer, single‐drug therapy has many limitations due to low …
Because of the heterogeneity of cancer, single‐drug therapy has many limitations due to low …
Recent advances in treatment of lung cancer: nanoparticle-based drug and siRNA delivery systems
A Gencer, C Duraloglu, S Ozbay, TT Ciftci… - Current drug …, 2021 - ingentaconnect.com
Lung cancer is the second most diagnosed cancer in both men and women worldwide.
Considering the high mortality rate of lung cancer and inadequacy of conventional treatment …
Considering the high mortality rate of lung cancer and inadequacy of conventional treatment …
[HTML][HTML] SiRNA conjugated nanoparticles—a next generation strategy to treat lung cancer
R Itani, A Al Faraj - International journal of molecular sciences, 2019 - mdpi.com
Despite major progress in both therapeutic and diagnostic techniques, lung cancer is still
considered the leading cause of cancer mortality in the world due to the ineffectiveness of …
considered the leading cause of cancer mortality in the world due to the ineffectiveness of …
Nanocarriers in effective pulmonary delivery of siRNA: current approaches and challenges
Research on siRNA is increasing due to its wide applicability as a therapeutic agent in
irreversible medical conditions. siRNA inhibits expression of the specific gene after its …
irreversible medical conditions. siRNA inhibits expression of the specific gene after its …
Fullerene-based nanocomplex assists pulmonary delivery of siRNA for treating metastatic lung cancer
Non-hepatic delivery of small interfering RNA (siRNA) remains a challenge for the
development of RNA interference (RNAi)-based therapeutics. Inhalation is a straightforward …
development of RNA interference (RNAi)-based therapeutics. Inhalation is a straightforward …
Nanoparticle‐mediated siRNA delivery and multifunctional modification strategies for effective cancer therapy
M Chen, C Dong, S Shi - Advanced Materials Technologies, 2021 - Wiley Online Library
RNA interference (RNAi), which can inhibit the expression or transcription of specific genes,
is considered to be a revolutionary tool for mediating gene therapy. Small interfering RNA …
is considered to be a revolutionary tool for mediating gene therapy. Small interfering RNA …
Tumor‐targeting multifunctional nanoparticles for siRNA delivery: Recent advances in cancer therapy
RNA interference (RNAi) is a naturally occurring regulatory process that controls
posttranscriptional gene expression. Small interfering RNA (siRNA), a common form of RNAi …
posttranscriptional gene expression. Small interfering RNA (siRNA), a common form of RNAi …
SiRNA-based therapies for pulmonary diseases
Various delivery strategies, involving siRNA as a therapeutic tool for gene silencing, have
been highlighted through several investigations all over the world. One such medical target …
been highlighted through several investigations all over the world. One such medical target …
[HTML][HTML] Multifunctional lipid-based nanoparticles for codelivery of anticancer drugs and siRNA for treatment of non-small cell lung cancer with different level of …
J Majumder, T Minko - Pharmaceutics, 2021 - mdpi.com
Resistance to chemotherapy, enhanced proliferation, invasion, angiogenesis, and
metastasis (RPIAM) represent major obstacles that limit the efficacy of cancer treatment …
metastasis (RPIAM) represent major obstacles that limit the efficacy of cancer treatment …