The fungal human pathogen Cryptococcus neoformans undergoes melanization in
response to nutrient starvation and exposure to exogenous melanin precursors …

Melanin is an antioxidant polyphenol pigment required for the pathogenicity of many fungal
pathogens, but comprehensive regulatory mechanisms remain unidentified. In this study, we …

Cryptococcosis is a common opportunistic fungal infection that often disseminates into the
central nervous system, leading to meningitis. Production of melanin pigments during …

The pathogenic fungus Cryptococcus neoformans produces melanin within its cell wall for
infection and resistance against external stresses such as exposure to UV, temperature …

Cryptococcus neoformans and Cryptococcus gattii are two species complexes in the large
fungal genus Cryptococcus and are responsible for potentially lethal disseminated …

Cryptococcus neoformans is unusual among melanotic fungi in that it requires an
exogenous supply of precursor to synthesize melanin. C. neoformans melanizes during …

Cryptococcus neoformans is a pathogenic fungus that produces melanin when incubated in
the presence of certain phenolic substrates such as l-3, 4-dihydroxyphenylalanine (l-dopa) …

The fungal pathogen Cryptococcus neoformans is well adapted to its host environment. It
has several defence mechanisms to evade oxidative and nitrosative agents released by …

Cryptococcus neoformans is a fungus that is pathogenic in humans and that can produce
melanin in vitro. Melanization is associated with virulence, but there is no evidence that …

The ability to produce melanin is a key virulence factor in many fungal pathogens including
the human basidiomycete pathogen Cryptococcus neoformans, a major cause of life …