Interleukin‐1 receptor antagonist levels correlate with extent of myocardial loss in patients with acute myocardial infarction

G Patti, S Mega, V Pasceri, A Nusca… - … Indexed and Peer …, 2005 - Wiley Online Library
Abstract Background: Interleukin‐1 receptor antagonist (IL‐1 Ra) levels are elevated early in
patients with acute myocardial infarction (MI) and often precede release of markers of …

Early interleukin-1 receptor antagonist elevation in patients with acute myocardial infarction

G Patti, A D'Ambrosio, S Mega, G Giorgi… - Journal of the American …, 2004 - jacc.org
Objectives: We sought to evaluate interleukin-1 receptor antagonist (IL-1Ra) levels in
patients with ST-segment elevation acute myocardial infarction (AMI) upon emergency …

Interleukin-1 receptor antagonist: a sensitive marker of instability in patients with coronary artery disease

G Patti, A D'Ambrosio, A Dobrina, G Dicuonzo… - Journal of thrombosis …, 2002 - Springer
Background: Increased plasma levels of acute phase reactants are correlated with acute
coronary syndromes and increased risk of in-hospital events. Interleukin-1 receptor …

Interleukin-1β and risk of premature death in patients with myocardial infarction

J Silvain, M Kerneis, M Zeitouni, B Lattuca… - Journal of the American …, 2020 - jacc.org
Background Inhibition of the interleukin (IL)-1β innate immunity pathway is associated with
anti-inflammatory effects and a reduced risk of recurrent cardiovascular events in stable …

Comparative safety of interleukin-1 blockade with anakinra in patients with ST-segment elevation acute myocardial infarction (from the VCU-ART and VCU-ART2 pilot …

A Abbate, MC Kontos, NA Abouzaki… - The American journal of …, 2015 - Elsevier
Two pilot studies of interleukin-1 (IL-1) blockade in ST-segment elevation myocardial
infarction (STEMI) showed blunted acute inflammatory response and overall favorable …

Soluble interleukin-2 receptor combined with interleukin-8 is a powerful predictor of future adverse cardiovascular events in patients with acute myocardial infarction

K Pan, C Xu, C Chen, S Chen, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Little is known about the role of interleukin (IL) in patients with acute myocardial
infarction (MI), especially soluble IL-2 receptor (sIL-2R) and IL-8. We aim to evaluate, in MI …

Interleukin‐1 blockade inhibits the acute inflammatory response in patients with ST‐segment–elevation myocardial infarction

A Abbate, CR Trankle, LF Buckley… - Journal of the …, 2020 - Am Heart Assoc
Background ST‐segment–elevation myocardial infarction is associated with an intense
acute inflammatory response and risk of heart failure. We tested whether interleukin‐1 …

Decreased soluble interleukin-6 receptor in patients with acute myocardial infarction

K Ueda, M Takahashi, K Ozawa, M Kinoshita - American heart journal, 1999 - Elsevier
Background: The plasma level of interleukin-6 (IL-6), a proinflammatory cytokine, has been
reported to be elevated in patients with acute myocardial infarction (AMI). In addition to a …

Increased interleukin‐1β levels are associated with left ventricular hypertrophy and remodelling following acute st segment elevation myocardial infarction treated by …

S Ørn, T Ueland, C Manhenke… - Journal of internal …, 2012 - Wiley Online Library
Ørn S, Ueland T, Manhenke C, Sandanger Ø, Godang K, Yndestad A, Mollnes TE, Dickstein
K, Aukrust P (Stavanger University Hospital, Stavanger; Oslo University Hospital …

Clinical and pharmacological implications of time to treatment with interleukin-1 blockade in ST-segment elevation myocardial infarction

MG Del Buono, JI Damonte, F Moroni… - … of Pharmacology and …, 2023 - ASPET
Interleukin-1 (IL-1) blockade with anakinra given within 12 hours from reperfusion has been
shown to reduce the inflammatory response as well as prevent heart failure (HF) events in …