Human exosomes accelerate cutaneous wound healing by promoting collagen synthesis in a diabetic mouse model

B Zhao, X Zhang, Y Zhang, Y Lu, W Zhang… - Stem Cells and …, 2021 - liebertpub.com
Chronic wounds including diabetic foot ulcers are clinical emergencies that need careful
management. Exosomes from human adipose-derived mesenchymal stem cells (hADSCs …

[HTML][HTML] Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

[HTML][HTML] Exosomes derived from epidermal stem cells improve diabetic wound healing

P Wang, G Theocharidis, IS Vlachos, K Kounas… - Journal of Investigative …, 2022 - Elsevier
Diabetic foot ulceration is a major diabetic complication with unmet needs. We investigated
the efficacy of epidermal stem cells and epidermal stem cells–derived exosomes (ESCs …

[HTML][HTML] Combined topical and systemic administration with human adipose-derived mesenchymal stem cells (hADSC) and hADSC-derived exosomes markedly …

Y Zhou, B Zhao, XL Zhang, Y Lu, ST Lu… - Stem cell research & …, 2021 - Springer
Background Cutaneous wound healing and regeneration have become a recognized health
challenge in the world, which causes severe damage to the mental and physical health of …

Exosomes derived from autologous dermal fibroblasts promote diabetic cutaneous wound healing through the Akt/β-catenin pathway

X Han, P Wu, L Li, HM Sahal, C Ji, J Zhang, Y Wang… - Cell Cycle, 2021 - Taylor & Francis
Diabetic cutaneous wounds are one of the complications of diabetes mellitus (DM) and are
difficult to cure at present. Autologous dermal fibroblasts (DFs) have shown great promise in …

[HTML][HTML] Therapeutic Potential of Exosomes Derived from Diabetic Adipose Stem Cells in Cutaneous Wound Healing of db/db Mice

HH Hsu, AYL Wang, CYY Loh, AA Pai, HK Kao - Pharmaceutics, 2022 - mdpi.com
(1) Background: Diabetes impairs angiogenesis and wound healing. Paracrine secretion
from adipose stem cells (ASCs) contains membrane-bound nano-vesicles called exosomes …

Promising effects of exosomes isolated from menstrual blood‐derived mesenchymal stem cell on wound‐healing process in diabetic mouse model

R Dalirfardouei, K Jamialahmadi… - Journal of Tissue …, 2019 - Wiley Online Library
Wound healing is a complicated process that contains a number of overlapping and
consecutive phases, disruption in each of which can cause chronic nonhealing wounds. In …

[HTML][HTML] Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration

Y Zhou, XL Zhang, ST Lu, NY Zhang, HJ Zhang… - Stem cell research & …, 2022 - Springer
Background Large area skin trauma has always been a great challenge for both patients
and clinicians. Exosomes originating from human adipose-derived mesenchymal stem cells …

[HTML][HTML] Adipose tissue-derived mesenchymal stem cell-derived exosomes promote wound healing and tissue regeneration

JH Lee, YJ Won, H Kim, M Choi, E Lee… - International Journal of …, 2023 - mdpi.com
Wound healing is a complex process involving cell proliferation, migration, and extracellular
matrix (ECM) remodeling. Extracellular vesicles (EVs) or exosomes derived from adipose …

[HTML][HTML] Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling

L Wang, L Hu, X Zhou, Z Xiong, C Zhang… - Scientific Reports, 2017 - nature.com
Scar formation is an intractable medical problem that appears after skin wounds have
healed. Recent research has shown that exosomes secreted by human adipose …