Anticancer and antioxidant phytochemicals as speed breakers in inflammatory signaling

PA Olajide, OA Adetuyi, OS Omowumi… - World News of Natural …, 2022 - yadda.icm.edu.pl
ABSTRACT A causal association between inflammation and cancer has long been
suspected. Multiple lines of compelling evidence from clinical, epidemiologic and laboratory …

[PDF][PDF] Preventive phytochemicals of cancer as speed breakers in inflammatory signaling

BO Adetuyi, PA Olajide, A Oluwatosin… - Research Journal of Life …, 2022 - rjlbpcs.com
A causal association between inflammation and cancer has long been suspected. Multiple
evidences from clinical, epidemiologic and laboratory studies support that inflammation …

Cancer preventive phytochemicals as speed breakers in inflammatory signaling involved in aberrant COX-2 expression

YJ Surh, JK Kundu - Current Cancer Drug Targets, 2007 - ingentaconnect.com
A causal association between inflammation and cancer has long been suspected. Multiple
lines of compelling evidence from clinical, epidemiologic and laboratory studies support that …

Signal transduction network leading to COX-2 induction: a road map in search of cancer chemopreventives

YJ Surh, JK Kundu - Archives of pharmacal research, 2005 - Springer
Cancer is still a major global health concern even after an everlasting strive in conquering
this dread disease. Emphasis is now given to chemoprevention to reduce the risk of cancer …

Mechanisms of phytonutrient modulation of cyclooxygenase-2 (COX-2) and inflammation related to cancer

SJ Desai, B Prickril, A Rasooly - Nutrition and cancer, 2018 - Taylor & Francis
The link between chronic inflammation and cancer involves cytokines and mediators of
inflammatory pathways. Cyclooxygenase-2 (COX-2), a key enzyme in fatty acid metabolism …

Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals

JK Kundu, YJ Surh - … Research/Fundamental and Molecular Mechanisms of …, 2005 - Elsevier
Center to the cancer biology is disrupted intracellular signaling network, which transmits
improper signals resulting in abnormal cellular functioning. Therefore, modulation of …

Role of ROS and COX-2/iNOS inhibition in cancer chemoprevention: a review

M Kumar, S Kumar, S Kaur - Phytochemistry Reviews, 2012 - Springer
Since the times immemorial, our ancestors have been using medicinal plants or their parts
for curing various ailments. The experiences of time have led to the strong system of …

Modulation of inflammatory genes by natural dietary bioactive compounds

MH Pan, CS Lai, S Dushenkov… - Journal of agricultural and …, 2009 - ACS Publications
Several epidemiologic studies have shown that chronic inflammation predisposes
individuals to various types of cancer. Many cancers arise from sites of infection, chronic …

[PDF][PDF] Targeting the key factors of inflammation in cancer: plant intervention

LO Linus, C Hanson, RN Alolga, W Zhou, L Qi - Int J Clin Exp Med, 2017 - researchgate.net
The association between inflammation and cancer has earned significant recognition and
acceptance. The activation of genes controlling inflammation cell signaling pathways can …

Transcription factors and mitogen-activated protein kinases as molecular targets for chemoprevention with anti-inflammatory phytochemicals

YJ Surh, HK Na, S Sei Lee - Biofactors, 2004 - content.iospress.com
Chemoprevention refers to the use of nontoxic chemical substances to inhibit, reverse, or
retard tumorigenesis. Numerous compounds derived from edible plants have been reported …