A canonical view of the primary physiological function of myoglobin (Mb) is that it is an
oxygen (O2) storage protein supporting mitochondrial oxidative phosphorylation, especially …

The identification of novel physiological regulators that stimulate energy expenditure
through brown adipose tissue (BAT) activity in substrate catalysis is of utmost importance to …

Myoglobin (Mb) regulates O2 bioavailability in muscle and heart as the partial pressure of
O2 (Po2) drops with increased tissue workload. Globin proteins also modulate cellular NO …

Myoglobin (Mb) is a regulator of O2 bioavailability in type I muscle and heart, at least when
tissue O2 levels drop. Mb also plays a role in regulating cellular nitric oxide (NO) pools …

Myoglobin (MB) belongs to the well-studied globin proteins superfamily. It has been
extensively studied for its physiological roles in oxygen storage and transport for about a …

Myoglobin (Mb) is an important intracellular oxygen-binding hemoprotein found in the
cytoplasm of skeletal and cardiac muscle tissue playing a well-known role in O2 storage and …

For more than 100 years, myoglobin has been among the most extensively studied proteins.
Since the first comprehensive review on myoglobin function as a dioxygen store by Millikan …

Recent studies of myoglobin (Mb) knockout (myo−/−) mice have extended our
understanding of Mb's diverse functions and have demonstrated a complex array of …

Myoglobin (Mb) is an oxygen-binding muscular hemeprotein regulated via Ca2+-signaling
pathways involving calcineurin (CN), with Mb increases attributed to hypoxia, exercise, and …

Brown adipose tissue (BAT) plays an important role in energy homeostasis by generating
heat from chemical energy via uncoupled oxidative phosphorylation. Besides its high …