Circ_0005699 participates in ox-LDL-induced human umbilical vein endothelial cell injury via targeting the miR-636/TLR4/NF-κB pathway

G Tao, C Zhong, L Zhang, X Zhong, X Li, Z Wang… - Biochemical …, 2022 - Elsevier
Background The vital roles of some circular RNA (circRNA) have been reported to be
associated with atherosclerosis (AS). In this paper, we explored the function of circ_0005699 …

[HTML][HTML] CircUSP36 knockdown alleviates oxidized low‑density lipoprotein‑induced cell injury and inflammatory responses in human umbilical vein endothelial cells …

J Miao, B Wang, R Shao… - … journal of molecular …, 2021 - spandidos-publications.com
The dysfunctions of human umbilical vein endothelial cells (HUVECs) are important features
of atherosclerosis (AS). Circular RNAs (circRNAs) are regulators of a wide range of human …

CircRNA circCOL1A1 acts as a sponge of miR-30a-5p to promote vascular smooth cell phenotype switch through regulation of Smad1 expression

M Ye, Q Ni, H Wang, Y Wang, Y Yao… - Thrombosis and …, 2023 - thieme-connect.com
Phenotypic switch of vascular smooth muscle cells (VSMCs) plays an important role in the
pathogenesis of atherosclerosis. The mRNA expression of the synthetic biomarker Collagen …

[HTML][HTML] circ_CHFR regulates ox-LDL-mediated cell proliferation, apoptosis, and EndoMT by miR-15a-5p/EGFR axis in human brain microvessel endothelial cells

S Wu, S Yang, H Qu - Open Life Sciences, 2021 - degruyter.com
Oxidized low-density lipoprotein (ox-LDL) is a significant risk factor for various brain vascular
diseases. Circular RNA (circRNA) is involved in the pathogenesis of brain vascular …

Circular RNA circ_0124644 exacerbates the ox-LDL-induced endothelial injury in human vascular endothelial cells through regulating PAPP-A by acting as a sponge …

G Wang, Y Li, Z Liu, X Ma, M Li, Q Lu, Y Li, Z Lu… - Molecular and cellular …, 2020 - Springer
The modulatory roles of numerous circular RNAs (circRNAs) have been exposited in
atherosclerosis (AS). Our study paid attention to the function of circRNA_ 0124644 …

A novel protein encoded by circLARP1B promotes the proliferation and migration of vascular smooth muscle cells by suppressing cAMP signaling

P Lu, J Fan, M Song, X Wang, B Li - Atherosclerosis, 2024 - Elsevier
Background and aims Circular RNA (circRNA) is closely related to atherosclerosis (AS)
incidence and progression, but its regulatory mechanism in AS needs further elucidation. AS …

[HTML][HTML] Circ-ABCA1 promotes oxidized low-density lipoprotein-induced inflammation and phenotypic switch in vascular smooth muscle cells

F Yu, JW Liu, X Wei - Clinics, 2024 - SciELO Brasil
Objectives Atherosclerosis (AS) is a chronic inflammatory disease of the arterial wall, in
which Human Vascular Smooth Muscle Cells (HVSMCs) are involved. Nevertheless, the …

CircLZIC regulates ox-LDL-induced HUVEC cell proliferation and apoptosis via Micro-330-5p/NOTCH2 axis in atherosclerosis

X Men, A Hu, T Xu - Clinical Hemorheology and …, 2024 - content.iospress.com
Atherosclerosis (AS) is a major chronic non-communicable disease and a primary cause of
cardiovascular disease. Recent studies have shown that circRNAs are potential epigenetic …

[HTML][HTML] circDENND1B participates in the antiatherosclerotic effect of IL-1β monoclonal antibody in mouse by promoting cholesterol efflux via miR-17-5p/Abca1 axis

F Xu, L Shen, H Chen, R Wang, T Zang… - Frontiers in Cell and …, 2021 - frontiersin.org
Inflammation is a crucial mediator of atherosclerosis, and several therapeutic methods that
focus on inflammatory cytokines, including interleukin-1β (IL-1β), have proven effective in …

Circ_robo2/mir-149 axis promotes the proliferation and migration of human aortic smooth muscle cells by activating NF-κB signaling

DS Lin, CY Zhang, L Li, GH Ye, LP Jiang… - Cytogenetic and Genome …, 2021 - karger.com
Atherosclerosis is the leading global cause of mortality. The occurrence of coronary artery
disease (CAD) is regulated by a diversity of pathways, including circRNAs. However, the …