[HTML][HTML] Polysaccharides from sporoderm‑removed spores of Ganoderma lucidum induce apoptosis in human gastric cancer cells via disruption of autophagic flux

J Zhong, L Fang, R Chen, J Xu, D Guo… - Oncology …, 2021 - spandidos-publications.com
The sporoderm‑broken spores of Ganoderma lucidum (G. lucidum) polysaccharide (BSGLP)
have been demonstrated to inhibit carcinogenesis in several types of cancer. However, to …

[HTML][HTML] Removing the sporoderm from the sporoderm-broken spores of Ganoderma lucidum improves the anticancer and immune-regulatory activity of the water …

L Fang, Q Zhao, C Guo, D Guo, Z Li, J Xu, C Guo… - Frontiers in …, 2022 - frontiersin.org
Plant-derived polysaccharides have demonstrated promising anti-cancer effects via immune-
regulatory activity. The aim of the current study was to compare the chemical property and …

[HTML][HTML] Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation

H Pan, Y Wang, K Na, Y Wang, L Wang, Z Li… - Cell death & …, 2019 - nature.com
Targeting autophagy may serve as a promising strategy for cancer therapy. Ganoderma
lucidum polysaccharide (GLP) has been shown to exert promising anti-cancer effects …

Ganoderma lucidum Polysaccharide Enzymatic Hydrolysate Suppresses the Growth of Human Colon Cancer Cells via Inducing Apoptosis

J Bai, J Xu, J Zhao, R Zhang - Cell Transplantation, 2020 - journals.sagepub.com
Ganoderma lucidum is a popular traditional Chinese medicine used in China to improve
health. Previous researches have revealed that the polysaccharide from G. lucidum could …

[HTML][HTML] Ganoderma lucidum spore polysaccharide inhibits the growth of hepatocellular carcinoma cells by altering macrophage polarity and induction of apoptosis

M Song, Z Li, H Gu, R Tang, R Zhang, Y Zhu… - Journal of Immunology …, 2021 - hindawi.com
Background. Ganoderma lucidum has certain components with known pharmacological
effects, including strengthening immunity and anti-inflammatory activity. G. lucidum seeds …

[HTML][HTML] Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum

ZE Liang, YJ Yi, YT Guo, RC Wang… - Molecular …, 2015 - spandidos-publications.com
Ganoderma lucidum polysaccharides (GLPs), which were purified from the medicinal herb
G. lucidum followed by ethanol precipitation, protein depletion using the Sevage assay …

[HTML][HTML] Antitumor and immunomodulatory effects of polysaccharides from broken-spore of Ganoderma lucidum

PY Wang, XL Zhu, ZB Lin - Frontiers in pharmacology, 2012 - frontiersin.org
The antitumor and immunomodulatory activity of broken-spore of Ganodermalucidum
polysaccharides (Gl-BSP) were investigated in vivo and in vitro. It was showed that Gl-BSP …

[HTML][HTML] Chemical Characterization and Antitumor Activities of Polysaccharide Extracted from Ganoderma lucidum

Z Liang, Y Yi, Y Guo, R Wang, Q Hu… - International journal of …, 2014 - mdpi.com
Ganoderma lucidum polysaccharide (GLP) is a biologically active substance reported to
possess anti-tumor ability. Nonetheless, the mechanisms of GLP-stimulated apoptosis are …

[HTML][HTML] Restoration of the tumor-suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

D Jiang, L Wang, T Zhao, Z Zhang… - Oncology …, 2017 - spandidos-publications.com
Ganoderma lucidum polysaccharides (GLPs), isolated from spores, mycelia and fruiting
bodies of Ganoderma lucidum, have been suggested to possess anticancer activities in a …

[HTML][HTML] Polysaccharide from spore of Ganoderma lucidum ameliorates paclitaxel-induced intestinal barrier injury: Apoptosis inhibition by reversing microtubule …

D Li, L Gao, M Li, Y Luo, Y Xie, T Luo, L Su… - Biomedicine & …, 2020 - Elsevier
Side effects of chemotherapy are burning questions for physicians and patients involved in
cancers. Ganoderma lucidum is a widely consumed traditional Chinese medicine and edible …