[HTML][HTML] Comparative analysis on abnormal methylome of differentially expressed genes and disease pathways in the immune cells of RA and SLE

Q Fang, T Li, P Chen, Y Wu, T Wang, L Mo… - Frontiers in …, 2021 - frontiersin.org
We identified abnormally methylated, differentially expressed genes (DEGs) and pathogenic
mechanisms in different immune cells of RA and SLE by comprehensive bioinformatics …

[HTML][HTML] Genome-wide DNA methylation profiles reveal common epigenetic patterns of interferon-related genes in multiple autoimmune diseases

S Chen, W Pu, S Guo, L Jin, D He, J Wang - Frontiers in genetics, 2019 - frontiersin.org
Graves' disease (GD), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and
systemic sclerosis (SSc) are complex autoimmune diseases sharing common clinical …

[HTML][HTML] Shared and unique patterns of DNA methylation in systemic lupus erythematosus and primary Sjögren's syndrome

J Imgenberg-Kreuz, JC Almlöf, D Leonard… - Frontiers in …, 2019 - frontiersin.org
Objectives: To perform a cross-comparative analysis of DNA methylation in patients with
systemic lupus erythematosus (SLE), patients with primary Sjögren's syndrome (pSS), and …

Identification of differentially expressed and methylated genes associated with rheumatoid arthritis based on network

D Zhang, ZF Li, RQ Zhang, XL Yang, DD Zhang… - …, 2020 - Taylor & Francis
Rheumatoid arthritis (RA) is a multi-systemic inflammatory autoimmune disease involving
peripheral joints, and the pathogenesis is not clear. Studies showed that DNA methylation …

[HTML][HTML] Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic …

H Zhu, W Mi, H Luo, T Chen, S Liu, I Raman… - Arthritis research & …, 2016 - Springer
Background Recent achievement in genetics and epigenetics has led to the exploration of
the pathogenesis of systemic lupus erythematosus (SLE). Identification of differentially …

Integration of Genome‐Wide DNA Methylation and Transcription Uncovered Aberrant Methylation‐Regulated Genes and Pathways in the Peripheral Blood …

H Zhu, C Zhu, W Mi, T Chen, H Zhao… - International Journal …, 2018 - Wiley Online Library
Objective. Systemic sclerosis (SSc) is a systemic connective tissue disease of unknown
etiology. Aberrant gene expression and epigenetic modifications in circulating immune cells …

[HTML][HTML] DNA methylation exploration for ARDS: a multi-omics and multi-microarray interrelated analysis

S Zhang, Z Wu, J Xie, Y Yang, L Wang… - Journal of Translational …, 2019 - Springer
Background Despite advances in clinical management, there are currently no novel
therapeutic targets for acute respiratory distress syndrome (ARDS). DNA methylation, as a …

Comprehensive analysis of epigenetic modifications and immune-cell infiltration in tissues from patients with systemic lupus erythematosus

Z He, S Zhou, M Yang, Z Zhao, Y Mei, Y Xin, M Zhao… - …, 2022 - Taylor & Francis
Aim: To explore potential abnormal epigenetic modifications and immune-cell infiltration in
tissues from systemic lupus erythematosus (SLE) patients. Materials & methods: To utilize …

[HTML][HTML] Genome-wide DNA methylation analysis of Chinese patients with systemic lupus erythematosus identified hypomethylation in genes related to the type I …

KS Yeung, BHY Chung, S Choufani, MY Mok… - PLoS …, 2017 - journals.plos.org
Background Epigenetic variants have been shown in recent studies to be important
contributors to the pathogenesis of systemic lupus erythematosus (SLE). Here, we report a 2 …

[HTML][HTML] Identification of potential biomarkers for psoriasis by DNA methylation and gene expression datasets

Y Liu, S Cui, J Sun, X Yan, D Han - Frontiers in Genetics, 2021 - frontiersin.org
DNA methylation (DNAm) plays an important role in the pathogenesis of psoriasis through
regulating mRNA expressions. This study aimed to identify hub genes regulated by DNAm …