Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ …
DM Absher, X Li, LL Waite, A Gibson, K Roberts… - PLoS …, 2013 - journals.plos.org
Systemic lupus erythematosus (SLE) is an autoimmune disease with known genetic,
epigenetic, and environmental risk factors. To assess the role of DNA methylation in SLE, we …
epigenetic, and environmental risk factors. To assess the role of DNA methylation in SLE, we …
Genome-wide DNA methylation patterns in CD4+ T cells from Chinese Han patients with rheumatoid arthritis
S Guo, Q Zhu, T Jiang, R Wang, Y Shen… - Modern …, 2017 - academic.oup.com
Introduction: Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic
inflammation of the joints. Recent evidence indicated the epigenetic changes may contribute …
inflammation of the joints. Recent evidence indicated the epigenetic changes may contribute …
DNA methylation in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease facilitated by
aberrant immune responses directed against cells and tissues, resulting in inflammation and …
aberrant immune responses directed against cells and tissues, resulting in inflammation and …
DNA methylome signature in rheumatoid arthritis
Objectives Epigenetics can influence disease susceptibility and severity. While DNA
methylation of individual genes has been explored in autoimmunity, no unbiased systematic …
methylation of individual genes has been explored in autoimmunity, no unbiased systematic …
Exploration of biomarkers of psoriasis through combined multiomics analysis
L Xing, T Wu, L Yu, N Zhou, Z Zhang… - Mediators of …, 2022 - Wiley Online Library
Background. Aberrant DNA methylation patterns are of increasing interest in the study of
psoriasis mechanisms. This study aims to screen potential diagnostic indicators affected by …
psoriasis mechanisms. This study aims to screen potential diagnostic indicators affected by …
Increased 5-hydroxymethylcytosine in CD4+ T cells in systemic lupus erythematosus
M Zhao, J Wang, W Liao, D Li, M Li, H Wu… - Journal of …, 2016 - Elsevier
One of the major disappointments in autoimmunity has been the relative lack of informative
data when genomewide associations (GWAS) have been applied to patients with systemic …
data when genomewide associations (GWAS) have been applied to patients with systemic …
Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren's syndrome
C Miceli-Richard, SF Wang-Renault… - Annals of the …, 2016 - ard.bmj.com
Background Beyond genetics, epigenetics alterations and especially those related to DNA
methylation, play key roles in the pathogenesis of autoimmune diseases such as primary …
methylation, play key roles in the pathogenesis of autoimmune diseases such as primary …
Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: identifying DNA methylation signatures associated with …
S Joseph, NI George, B Green-Knox, EL Treadwell… - Journal of …, 2019 - Elsevier
Systemic lupus erythematosus (SLE or lupus) is a heterogeneous autoimmune disease
characterized by the involvement of multiple organs and the production of antinuclear …
characterized by the involvement of multiple organs and the production of antinuclear …
Genome-wide DNA methylation patterns in monocytes derived from patients with primary Sjogren syndrome
X Luo, Y Peng, YY Chen, AQ Wang… - Chinese Medical …, 2021 - mednexus.org
Background: Epigenetics, especially DNA methylation, plays an important role in the
pathogenesis of primary Sjogren syndrome (pSS). Our study aimed to reveal the role of DNA …
pathogenesis of primary Sjogren syndrome (pSS). Our study aimed to reveal the role of DNA …
Genome-wide analysis of 5-hmC in the peripheral blood of systemic lupus erythematosus patients using an hMeDIP-chip
W Sui, Q Tan, M Yang, Q Yan… - International …, 2015 - spandidos-publications.com
Systemic lupus erythematosus (SLE) is a chronic, potentially fatal systemic autoimmune
disease characterized by the production of autoantibodies against a wide range of self …
disease characterized by the production of autoantibodies against a wide range of self …