Genome‐wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome
Objective Primary Sjögren's syndrome (SS) is a systemic autoimmune disease with
incompletely understood etiology. This study was undertaken to investigate the role of …
incompletely understood etiology. This study was undertaken to investigate the role of …
Associations between the expression of epigenetically regulated genes and the expression of DNMTs and MBDs in systemic lupus erythematosus
E Balada, J Castro-Marrero, L Felip, J Ordi-Ros… - 2012 - journals.plos.org
Objectives We determined the expression of ITGAL, PRF1, KIR2DL4, CD70, and CD40LG in
patients with SLE and performed correlations with the global DNA methylation status and the …
patients with SLE and performed correlations with the global DNA methylation status and the …
DNA methylation patterns in CD4+ T-cells separate psoriasis patients from healthy controls, and skin psoriasis from psoriatic arthritis
V Natoli, A Charras, SR Hofmann, S Northey… - Frontiers in …, 2023 - frontiersin.org
Background Psoriasis is an autoimmune/inflammatory disorder primarily affecting the skin.
Chronic joint inflammation triggers the diagnosis of psoriatic arthritis (PsA) in approximately …
Chronic joint inflammation triggers the diagnosis of psoriatic arthritis (PsA) in approximately …
Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis
M Hudson, S Bernatsky, I Colmegna, M Lora… - Epigenetics, 2017 - Taylor & Francis
We undertook this study to identify DNA methylation signatures of three systemic
autoimmune rheumatic diseases (SARDs), namely rheumatoid arthritis, systemic lupus …
autoimmune rheumatic diseases (SARDs), namely rheumatoid arthritis, systemic lupus …
Mendelian randomization analysis revealed potential causal factors for systemic lupus erythematosus
X Mo, Y Guo, Q Qian, M Fu, S Lei, Y Zhang… - …, 2020 - Wiley Online Library
Genome‐wide association studies (GWAS) have identified many loci for systemic lupus
erythematosus (SLE). However, identification of functionally relevant genes remains a …
erythematosus (SLE). However, identification of functionally relevant genes remains a …
The key culprit in the pathogenesis of systemic lupus erythematosus: aberrant DNA methylation
H Wu, M Zhao, L Tan, Q Lu - Autoimmunity reviews, 2016 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ
involvement. It is characterized by abundant autoantibodies that form immune complex with …
involvement. It is characterized by abundant autoantibodies that form immune complex with …
A whole genome methylation analysis of systemic lupus erythematosus: hypomethylation of the IL10 and IL1R2 promoters is associated with disease activity
The etiology of systemic lupus erythematosus (SLE) involves a complex interaction of
genetic and environmental factors. Investigations have shown that environmentally driven …
genetic and environmental factors. Investigations have shown that environmentally driven …
Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus
G Guo, H Wang, X Shi, L Ye, K Yan, Z Chen… - Frontiers in cell and …, 2020 - frontiersin.org
Epigenetic processes including RNA methylation, post-translational modifications, and non-
coding RNA expression have been associated with the heritable risks of systemic lupus …
coding RNA expression have been associated with the heritable risks of systemic lupus …
Genome-wide assessment of differential DNA methylation associated with autoantibody production in systemic lupus erythematosus
SA Chung, J Nititham, E Elboudwarej, HL Quach… - PloS one, 2015 - journals.plos.org
Systemic lupus erythematosus (SLE) is characterized by the development of autoantibodies
associated with specific clinical manifestations. Previous studies have shown an association …
associated with specific clinical manifestations. Previous studies have shown an association …
Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus
Systemic lupus erythematosus is a chronic-relapsing autoimmune disease of incompletely
understood etiology. Recent evidence strongly supports an epigenetic contribution to the …
understood etiology. Recent evidence strongly supports an epigenetic contribution to the …