[HTML][HTML] Increased HERV-E clone 4–1 expression contributes to DNA hypomethylation and IL-17 release from CD4+ T cells via miR-302d/MBD2 in systemic lupus …
X Wang, C Zhao, C Zhang, X Mei, J Song… - Cell Communication and …, 2019 - Springer
Background Increased human endogenous retroviruses E clone 4–1 (HERV-E clone 4–1)
mRNA expression is observed in systemic lupus erythematosus (SLE) patients and …
mRNA expression is observed in systemic lupus erythematosus (SLE) patients and …
[PDF][PDF] Genome-wide analysis of histone H3 lysine 4 trimethylation by ChIP-chip in peripheral blood mononuclear cells of systemic lupus erythematosus patients
Objective Histone H3 lysine 4 trimethylation (H3K4me3) is an important epigenetic
modification and associated with active transcription in multiple organisms. In systemic lupus …
modification and associated with active transcription in multiple organisms. In systemic lupus …
[HTML][HTML] Revealing the immune heterogeneity between systemic lupus erythematosus and rheumatoid arthritis based on multi-omics data analysis
The pathogenesis of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are
greatly influenced by different immune cells. Nowadays both T-cell receptor (TCR) and B …
greatly influenced by different immune cells. Nowadays both T-cell receptor (TCR) and B …
[HTML][HTML] An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype
JW Whitaker, R Shoemaker, DL Boyle, J Hillman… - Genome medicine, 2013 - Springer
Background A DNA methylation signature has been characterized that distinguishes
rheumatoid arthritis (RA) fibroblast like synoviocytes (FLS) from osteoarthritis (OA) FLS. The …
rheumatoid arthritis (RA) fibroblast like synoviocytes (FLS) from osteoarthritis (OA) FLS. The …
[HTML][HTML] Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer
J Liu, H Li, L Sun, Z Wang, C Xing, Y Yuan - Cancer Cell International, 2017 - Springer
Background Methylation plays an important role in the etiology and pathogenesis of
colorectal cancer (CRC). This study aimed to identify aberrantly methylated-differentially …
colorectal cancer (CRC). This study aimed to identify aberrantly methylated-differentially …
Epigenetic variability in systemic lupus erythematosus: what we learned from genome-wide DNA methylation studies
M Teruel, AH Sawalha - Current rheumatology reports, 2017 - Springer
Purpose of Review DNA methylation has emerged as an important contributing factor in the
pathogenesis of systemic lupus erythematosus (SLE). Here, we describe the DNA …
pathogenesis of systemic lupus erythematosus (SLE). Here, we describe the DNA …
[HTML][HTML] Hypomethylation of HLA-DRB1 and its clinical significance in psoriasis
W Zong, Y Ge, Y Han, X Yang, Q Li, M Chen - Oncotarget, 2017 - ncbi.nlm.nih.gov
Increasing evidences indicate that the abnormal DNA methylation is involved in the
pathogenesis of psoriasis. A number of SNPs in HLA-DRB1 have been found being …
pathogenesis of psoriasis. A number of SNPs in HLA-DRB1 have been found being …
[HTML][HTML] DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneity
CM Lanata, SA Chung, LA Criswell - Lupus science & medicine, 2018 - lupus.bmj.com
SLE is a complex autoimmune disease that results from the interplay of genetics,
epigenetics and environmental exposures. DNA methylation is an epigenetic mechanism …
epigenetics and environmental exposures. DNA methylation is an epigenetic mechanism …
Genome‐wide expression and methylation profiles reveal candidate genes and biological processes underlying synovial inflammatory tissue of patients with …
J Yang, N Wang - International journal of rheumatic diseases, 2015 - Wiley Online Library
Aim The aim of the study was to identify osteoarthritis (OA)‐related biological markers and
processes. Methods The gene expression profile GSE 46750 including 12 normal and 12 …
processes. Methods The gene expression profile GSE 46750 including 12 normal and 12 …
DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype
M Zhao, S Liu, S Luo, H Wu, M Tang, W Cheng… - Journal of …, 2014 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease well known for its clinical
heterogeneity, and its etiology secondary to a cross-talk involving genetic predisposition and …
heterogeneity, and its etiology secondary to a cross-talk involving genetic predisposition and …