Matrix metalloproteinases (MMPs) are postulated to be necessary for neovascularization
during wound healing. MMP-9 deletion alters remodeling postmyocardial infarction (post …

Background Fibrosis is a pivotal event in infarct repair and progressive remodeling after
myocardial infarction (MI). Biomarkers may be used to monitor fibrosis, and therefore we …

Background: Optimal healing of the myocardium after myocardial infarction (MI) requires a
suitable degree of inflammation and its timely resolution, together with a well-orchestrated …

Purpose We evaluated a dimeric RGD-peptide,[68 Ga] DOTA-E-[c (RGDfK)] 2, for positron
emission tomography (PET) imaging of myocardial integrin expression associated with …

Background—Myocardial reperfusion after ischemia (I/R), although an effective approach in
rescuing the ischemic myocardium, can itself trigger several adverse effects including …

Myocardial infarction is the leading cause of death and disability worldwide, and the
development of new treatments can help reduce the size of myocardial infarction and …

Purpose The α v β 3 integrin is expressed in angiogenic vessels and is a potential target for
molecular imaging of evolving pathological processes. Its expression is upregulated in …

Objective:: Transforming growth factor (TGF)-β promotes the deposition of extracellular
matrix protein and also acts as an anti-inflammatory cytokine. These biological effects might …

Background—Left ventricular (LV) remodeling is associated with the development of heart
failure after myocardial infarction. Here we investigated whether integrin-linked kinase (ILK) …

Objectives Despite modern reperfusion therapies, left ventricular remodelling (LVR) occurs
frequently after an ST-elevated myocardial infarction (STEMI) and represents a strong …