Preclinical models of myocardial infarction: from mechanism to translation
TP Martin, EA MacDonald… - British Journal of …, 2022 - Wiley Online Library
Approximately 7 million people are affected by acute myocardial infarction (MI) each year,
and despite significant therapeutic and diagnostic advancements, MI remains a leading …
and despite significant therapeutic and diagnostic advancements, MI remains a leading …
Guidelines for in vivo mouse models of myocardial infarction
Despite significant improvements in reperfusion strategies, acute coronary syndromes all too
often culminate in a myocardial infarction (MI). The consequent MI can, in turn, lead to …
often culminate in a myocardial infarction (MI). The consequent MI can, in turn, lead to …
Animal models of myocardial infarction: Mainstay in clinical translation
Preclinical models with high prognostic power are a prerequisite for translational research.
The closer the similarity of a model to myocardial infarction (MI), the higher is the prognostic …
The closer the similarity of a model to myocardial infarction (MI), the higher is the prognostic …
[HTML][HTML] Current status and limitations of myocardial infarction large animal models in cardiovascular translational research
HS Shin, HH Shin, Y Shudo - Frontiers in bioengineering and …, 2021 - frontiersin.org
Establishing an appropriate disease model that mimics the complexities of human
cardiovascular disease is critical for evaluating the clinical efficacy and translation success …
cardiovascular disease is critical for evaluating the clinical efficacy and translation success …
Considerations for the bioengineering of advanced cardiac in vitro models of myocardial infarction
Despite the latest advances in cardiovascular biology and medicine, myocardial infarction
(MI) remains one of the major causes of deaths worldwide. While reperfusion of the …
(MI) remains one of the major causes of deaths worldwide. While reperfusion of the …
Rat models of myocardial infarction
R Bhindi, PK Witting, AC McMahon… - Thrombosis and …, 2006 - thieme-connect.com
Animal models of cardiovascular pathology contribute towards understanding and treatment
of a broad range of conditions. Specifically in the context of acute myocardial infarction …
of a broad range of conditions. Specifically in the context of acute myocardial infarction …
Models of myocardial ischemia
K Ytrehus - Drug Discovery Today: Disease Models, 2006 - Elsevier
The heart is highly dependent on aerobic metabolism. Given the widespread occurrence of
coronary atherosclerosis in the human, myocardial ischemia is a huge clinical problem …
coronary atherosclerosis in the human, myocardial ischemia is a huge clinical problem …
Guidelines for experimental models of myocardial ischemia and infarction
Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial
ischemia with or without reperfusion, and basic and translational research is needed to …
ischemia with or without reperfusion, and basic and translational research is needed to …
Myocardial infarction and intramyocardial injection models in swine
FC McCall, KS Telukuntla, V Karantalis, VY Suncion… - Nature protocols, 2012 - nature.com
Sustainable and reproducible large animal models that closely replicate the clinical
sequelae of myocardial infarction (MI) are important for the translation of basic science …
sequelae of myocardial infarction (MI) are important for the translation of basic science …
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on …
J van der Velden, FW Asselbergs… - Cardiovascular …, 2022 - academic.oup.com
Cardiovascular diseases represent a major cause of morbidity and mortality, necessitating
research to improve diagnostics, and to discover and test novel preventive and curative …
research to improve diagnostics, and to discover and test novel preventive and curative …