Reaching the last mile: main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa

G Gebrezgabiher, Z Mekonnen… - Infectious diseases of …, 2019 - mednexus.org
Background: Onchocerciasis (river blindness), caused by the filarial worm species
Onchocerca volvulus, is a serious vector-borne neglected tropical disease (NTD) of public …

Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes

Y Dadzie, UV Amazigo, BA Boatin… - Infectious Diseases of …, 2018 - mednexus.org
Background: Onchocerciasis is found predominantly in Africa where large scale vector
control started in 1974. Registration and donation of ivermectin by Merck & Co in 1987 …

Neglected tropical diseases in Africa: a new paradigm

AD Hopkins - International health, 2016 - academic.oup.com
Programmes to control onchocerciasis have been ongoing for over 40 years. What was once
a devastating blinding and disabling disease, particularly in West Africa, has largely been …

Onchocerciasis: shifting the target from control to elimination requires a new first-step—elimination mapping

MP Rebollo, H Zoure, K Ogoussan… - International …, 2018 - academic.oup.com
The meaning of 'mapping'in relation to onchocerciasis has changed at least three times over
the past 50 years as the programmatic goals and the assessment tools have changed. With …

Onchocerciasis elimination: progress and challenges

T Lakwo, D Oguttu, T Ukety, R Post… - Research and Reports …, 2020 - Taylor & Francis
Onchocerciasis is a parasitic infection caused by the filarial nematode Onchocerca volvulus
and transmitted through the bites of black flies of the genus Similium that breed in rivers and …

[HTML][HTML] Progress towards onchocerciasis elimination in the participating countries of the African Programme for Onchocerciasis Control: epidemiological evaluation …

AH Tekle, HGM Zouré, M Noma, M Boussinesq… - Infectious Diseases of …, 2016 - Springer
Abstract Background The African Programme for Onchocerciasis Control (APOC) was
created in 1995 to establish community-directed treatment with ivermectin (CDTi) in order to …

[HTML][HTML] Feasibility of onchocerciasis elimination with ivermectin treatment in endemic foci in Africa: first evidence from studies in Mali and Senegal

L Diawara, MO Traoré, A Badji, Y Bissan… - PLoS neglected …, 2009 - journals.plos.org
Background Mass treatment with ivermectin is a proven strategy for controlling
onchocerciasis as a public health problem, but it is not known if it can also interrupt …

[HTML][HTML] The future of onchocerciasis control in Africa

C Hodgkin, DH Molyneux, A Abiose… - PLoS Neglected …, 2007 - journals.plos.org
Large-scale control of onchocerciasis commenced over three decades ago, initially through
the Onchocerciasis Control Programme in West Africa (OCP, 1974–2002), and more …

Progress towards the elimination of onchocerciasis as a public-health problem in Uganda: opportunities, challenges and the way forward

R Ndyomugyenyi, T Lakwo… - Annals of Tropical …, 2007 - Taylor & Francis
The national onchocerciasis-control programme in Uganda successfully eliminated
Simulium neavei ss from the Itwara focus in 1997, by monthly ground spraying with larvicidal …

[HTML][HTML] Research for new drugs for elimination of onchocerciasis in Africa

AC Kuesel - International Journal for Parasitology: Drugs and Drug …, 2016 - Elsevier
Onchocerciasis is a parasitic, vector borne disease caused by the filarial nematode
Onchocerca volvulus. More than 99% of the population at risk of infection live in Africa …