It is well known that biomaterials topography can influence the behavior of stem cells.
Nevertheless, the fundamentals and the impact of nanoscale topography are just emerging …

Current load-bearing orthopaedic implants are produced in 'bio-inert'materials such as
titanium alloys. When inserted into the reamed bone during hip or knee replacement surgery …

Mesenchymal stem cells and 3D biomaterials are a potent assembly in tissue engineering.
Today, a sizable number of biomaterials has been characterized for special tissue …

Mechanical cues are widely used for regulating cell behavior because of their overarching,
extensive, and non‐invasive advantages. However, unlike chemical cues, mechanical cues …

Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …

Both chemical and mechanical stimuli can dramatically influence cell behavior. By
optimizing the signals cells experience, it may be possible to control the behavior of …

This review is designed to introduce the cytoskeleton and then discuss how mechanical
forces may be transduced to the cell nucleus. In addition to this, it also tries to explain current …

The generation of cell gradients is critical for understanding many biological systems and
realizing the unique functionality of many implanted biomaterials. However, most previous …

It is widely accepted that stem cells directly sense the elasticity of two-dimensional (2-D)
substrates and differentiate into a distinct cell type dependent on the substrate elasticity …

This work investigates the effect of surface topography and biomaterial wettability on protein
absorption, cell attachment, proliferation and morphology and reveals important insights in …