Background Alpha-2u globulin nephropathy mainly shows toxicological pathology only in
male rats induced by certain chemicals and drugs, such as levamisole (antiparasitic and …

Diabetic nephropathy (DN) is the leading cause of chronic kidney disease. Animal models
are essential tools for designing new strategies to prevent DN. C57Bl/6 (B6) mice are widely …

Background Diabetic nephropathy (DN) represents a microvascular complication of diabetes
mellitus (DM). Despite the increasing incidence and prevalence of DN, conservative therapy …

The mechanism of autophagy in diabetic nephropathy (DN) is still unclear. The study was
performed on streptozotocin (STZ) rats to investigate whether programmed cell death …

Background: Diabetic nephropathy (DN) has become one of the most common causes of
end stage renal disease (ESRD). Hyperglycemia induces oxidative stress in renal tubular …

To investigate whether aminoguanidine ameliorates streptozotocin-induced renal oxidative
stress and inflammation in diabetic mice. Diabetic nephropathy is characterized by structural …

Can murine diabetic nephropathy be separated from superimposed acute renal failure?
Background Streptozotocin (STZ) is commonly used to induce diabetes in experimental …

Aim. In this study, we aimed to investigate the effects of febuxostat, a novel inhibitor of
xanthine oxidase (XO), on renal damage in streptozotocin-(STZ-) induced diabetic rats …

Gene expression profile in streptozotocin-induced diabetic mice kidneys undergoing
glomerulosclerosis. Background To elucidate the molecular mechanism of diabetic …

Background: Chemical agents such as streptozotocin (STZ) and nicotinamide (NAD) are
used in animal models of diabetes mellitus and their related consequences in the kidneys …