Protective effects of luteolin on diabetic nephropathy in STZ‐induced diabetic rats
GG Wang, XH Lu, W Li, X Zhao… - … and Alternative Medicine, 2011 - Wiley Online Library
Diabetic nephropathy is a long‐term complication of diabetic mellitus. Many experimental
evidences suggest that persistent hyperglycaemia generates intracellular reactive oxygen …
evidences suggest that persistent hyperglycaemia generates intracellular reactive oxygen …
NCI-Black-Reiter (NBR) male rats fail to develop renal disease following exposure to agents that induce α-2u-globulin (α2u) nephropathy
DR Dietrich, JA Swenberg - Fundamental and applied toxicology, 1991 - Elsevier
Abstract The NCI-Black-Reiter (NBR) rat is the only strain of male rat known not to
synthesize the hepatic form of the low molecular weight protein, α 2u-globulin. In previous …
synthesize the hepatic form of the low molecular weight protein, α 2u-globulin. In previous …
Inhibition of renal tubular epithelial mesenchymal transition and endoplasmic reticulum stress-induced apoptosis with Shenkang injection attenuates diabetic …
WW Wang, YL Liu, MZ Wang, H Li, BH Liu… - Frontiers in …, 2021 - frontiersin.org
Background: The proximal renal tubule plays a critical role in diabetic kidney disease (DKD)
progression. Early glomerular disease in DKD triggers a cascade of injuries resulting in …
progression. Early glomerular disease in DKD triggers a cascade of injuries resulting in …
Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis
DJ Gong, L Wang, YY Yang, JJ Zhang, XH Liu - Renal failure, 2019 - Taylor & Francis
Diabetic patients are more susceptible to renal ischemia/reperfusion (I/R) injury (RI/RI) and
have a poor prognosis, but the underlying mechanism remains unclear. The present study …
have a poor prognosis, but the underlying mechanism remains unclear. The present study …
[PDF][PDF] Renal ischemia/reperfusion injury in type II DM: possible role of proinflammatory cytokines, apoptosis, and nitric oxide
Diabetes mellitus (DM) especially type II is a major health problem and diabetic nephropathy
is the main cause of end stage renal disease (ESRD). Renal ischemia/reperfusion (I/R) …
is the main cause of end stage renal disease (ESRD). Renal ischemia/reperfusion (I/R) …
Renoprotection of Danshen Injection on streptozotocin-induced diabetic rats, associated with tubular function and structure
DK Yin, JJ Yin, Y Yang, S Chen, XD Gao - Journal of Ethnopharmacology, 2014 - Elsevier
Abstract Ethnopharmacological relevance Danshen Injection, the aqueous extracts of Radix
Salvia miltiorrhiza (S. miltiorrhiza), is one of the most commonly used traditional Chinese …
Salvia miltiorrhiza (S. miltiorrhiza), is one of the most commonly used traditional Chinese …
Effect of oral berberine administration on the renal profiles of adenosine deaminase, arginase, and nitric oxide in streptozotocin-induced diabetic nephropathy of rats
Berberine (BBR) administration is effective in the management of diabetic nephropathy, but
the full mechanism of action has not been comprehensively established. This study …
the full mechanism of action has not been comprehensively established. This study …
Accelerated glomerulosclerosis in diabetic rats with immune complex injury
CK Abrass, AH Cohen - Diabetes, 1987 - Am Diabetes Assoc
Immune complex-mediated injury has been postulated to contribute to diabetic
microangiopathy. To test this hypothesis, immune complex disease was induced in both …
microangiopathy. To test this hypothesis, immune complex disease was induced in both …
Enrichment of Bioactive Lipids in Urinary Extracellular Vesicles and Evidence of Apoptosis in Kidneys of Hypertensive Diabetic Cathepsin B Knockout Mice after …
WC Schramm, N Bala, T Arekar, Z Malik, KM Chacko… - Biomedicines, 2024 - mdpi.com
Cathepsin B (CtsB) is a ubiquitously expressed cysteine protease that plays important roles
in health and disease. Urinary extracellular vesicles (uEVs) are released from cells …
in health and disease. Urinary extracellular vesicles (uEVs) are released from cells …
Toll-like receptor 4 is involved in a protective effect of rhein on immunoglobulin A nephropathy
X Chen, S Peng, H Zeng, A Fu… - Indian Journal of …, 2015 - journals.lww.com
Objectives: The objective was to investigate the protective effects of rhein on renal histology
change and the effects of rhein on renal tissue toll-like receptor (TLR) 4, TLR9, transforming …
change and the effects of rhein on renal tissue toll-like receptor (TLR) 4, TLR9, transforming …