Objective To understand the relationship between steroid hormones synthesized by the
gonads and colorectal cancer as well as its tumor microenvironment, in the expectation of …

Several epidemiological studies have reported that the use of female sex steroid hormones
could reduce the risk of colon cancer (CRC). This review summarizes the available data …

Preclinical and clinical data suggest a protective role for estrogens on colon cancer (CRC)
risk. estrogen receptor (ER) β is the prevalent ER in normal colonic mucosa, whereas its …

Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …

Gender difference in the incidence of colorectal cancer is well known and has been
supported by various epidemiologic studies. In Korea, women have lower incidence of …

Background Estrogen receptor β (ERβ) is a potential tumor-suppressor gene in colorectal
cancer (CRC). This hypothesis is supported by clinical and laboratory observations. Aim In …

Objective The different incidence of colorectal cancer between the sexes suggests that sex
hormones may be involved in the susceptibility to colorectal cancer. The association …

Colorectal cancer (CRC) is one of the most common types of cancers worldwide. The
incidence of sporadic CRC is lower in individuals below 50 years and increases with age …

Objective: To investigate the effects of medroxyprogesterone acetate on colon cancer cells
in vitro. Design: HT29 and HCT116 human colon cancer cell lines were used in this study …

Background: incidence of Colorectal cancer (CRC) is increasing globally. In Egypt, CRC
ranks the sixth most common cancer in males and the fifth in females. Aim: To assess the …