Role of gonadally synthesized steroid hormones in the colorectal cancer microenvironment
L Wenxuan, L Liu, L Zhang, Z Qiu, Z Wu… - Frontiers in …, 2023 - frontiersin.org
Objective To understand the relationship between steroid hormones synthesized by the
gonads and colorectal cancer as well as its tumor microenvironment, in the expectation of …
gonads and colorectal cancer as well as its tumor microenvironment, in the expectation of …
Therapeutic strategies and potential actions of female sex steroid hormones and their receptors in Colon cancer based on preclinical studies
AA Mahbub - Life, 2022 - mdpi.com
Several epidemiological studies have reported that the use of female sex steroid hormones
could reduce the risk of colon cancer (CRC). This review summarizes the available data …
could reduce the risk of colon cancer (CRC). This review summarizes the available data …
Prognostic relevance of estrogen receptor-α Ser167 phosphorylation in stage II-III colon cancer patients
I López-Calderero, A Carnero, A Astudillo, J Palacios… - Human pathology, 2014 - Elsevier
Preclinical and clinical data suggest a protective role for estrogens on colon cancer (CRC)
risk. estrogen receptor (ER) β is the prevalent ER in normal colonic mucosa, whereas its …
risk. estrogen receptor (ER) β is the prevalent ER in normal colonic mucosa, whereas its …
[HTML][HTML] Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness
Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …
Gender-specific colorectal cancer: epidemiologic difference and role of estrogen
HM Kim, HS Kim - The Korean Journal of Gastroenterology, 2014 - synapse.koreamed.org
Gender difference in the incidence of colorectal cancer is well known and has been
supported by various epidemiologic studies. In Korea, women have lower incidence of …
supported by various epidemiologic studies. In Korea, women have lower incidence of …
Estrogen receptor β expression and colorectal cancer: a systematic review and meta-analysis
Y Niv - European journal of gastroenterology & hepatology, 2015 - journals.lww.com
Background Estrogen receptor β (ERβ) is a potential tumor-suppressor gene in colorectal
cancer (CRC). This hypothesis is supported by clinical and laboratory observations. Aim In …
cancer (CRC). This hypothesis is supported by clinical and laboratory observations. Aim In …
[HTML][HTML] Sex hormones and genetic variants in hormone metabolic pathways associated with the risk of colorectal cancer
S Li, Y Chen, L Xie, Y Meng, L Zhu, H Chu, D Gu… - Environment …, 2020 - Elsevier
Objective The different incidence of colorectal cancer between the sexes suggests that sex
hormones may be involved in the susceptibility to colorectal cancer. The association …
hormones may be involved in the susceptibility to colorectal cancer. The association …
Potential role of estrogens in colorectal tumour development
K Leiszter, O Galamb, A Kalmár, S Zsigrai, G Valcz… - Orvosi hetilap, 2020 - europepmc.org
Colorectal cancer (CRC) is one of the most common types of cancers worldwide. The
incidence of sporadic CRC is lower in individuals below 50 years and increases with age …
incidence of sporadic CRC is lower in individuals below 50 years and increases with age …
Medroxyprogesterone acetate inhibits proliferation of colon cancer cell lines by modulating cell cycle-related protein expression
Y Tanaka, K Kato, R Mibu, S Uchida, K Asanoma… - Menopause, 2008 - journals.lww.com
Objective: To investigate the effects of medroxyprogesterone acetate on colon cancer cells
in vitro. Design: HT29 and HCT116 human colon cancer cell lines were used in this study …
in vitro. Design: HT29 and HCT116 human colon cancer cell lines were used in this study …
[HTML][HTML] Lack of estrogen receptors expression in malignant and pre-malignant colorectal lesions in Egyptian patients
Background: incidence of Colorectal cancer (CRC) is increasing globally. In Egypt, CRC
ranks the sixth most common cancer in males and the fifth in females. Aim: To assess the …
ranks the sixth most common cancer in males and the fifth in females. Aim: To assess the …