Estrogen and colorectal cancer incidence and mortality

S Lavasani, RT Chlebowski, RL Prentice, I Kato… - Cancer, 2015 - Wiley Online Library
BACKGROUND The preponderance of observational studies describe an association
between the use of estrogen alone and a lower incidence of colorectal cancer. In contrast …

Estrogen receptor β as a prognostic marker of tumor progression in colorectal cancer with familial adenomatous polyposis and sporadic polyps

PR Stevanato Filho, S Aguiar Junior… - Pathology & Oncology …, 2018 - Springer
The incidence of colorectal cancer (CRC) is lower in women than in men, and sex steroids
can be considered contributing factors because oral contraception usage and estrogen …

Reproductive factors and colorectal cancer risk. Case-control study

A Ruseva, R Lazarova, I Kosturkov… - Journal of IMAB …, 2015 - journal-imab-bg.org
Colorectal cancer is one of the most common cancers worldwide. The role of the female sex
hormones in the etiology of the disease is very intriguing. Reproductive factors are surrogate …

Sex-specific differences in the expression levels of estrogen receptor subtypes in colorectal cancer

NC Nüssler, K Reinbacher, N Shanny, A Schirmeier… - Gender medicine, 2008 - Elsevier
Background: Altered expression of estrogen receptors alpha and beta (ERα and ERβ) has
been hypothesized to play a role in carcinogenesis. However, little is known about the sex …

Reproductive history and risk of colorectal cancer in postmenopausal women

A Zervoudakis, HD Strickler, Y Park… - Journal of the …, 2011 - academic.oup.com
Background There are conflicting data regarding the role of sex hormones in colorectal
cancer development. Whereas clinical trials data indicate that hormone therapy use reduces …

Subsite-specific differences of estrogen receptor beta expression in the normal colonic epithelium: implications for carcinogenesis and colorectal cancer epidemiology

K Papaxoinis, K Triantafyllou, AJ Sasco… - European journal of …, 2010 - journals.lww.com
Objective This study aimed at investigating whether a differential estrogen receptor beta (ER-
β) expression between the colonic subsites could correspond to a modification in …

Oestrogen receptor-related receptor alpha (ERRα) and oestrogen receptors (ERα and ERβ) exhibit different gene expression in human colorectal tumour progression

A Cavallini, M Notarnicola, R Giannini… - European journal of …, 2005 - Elsevier
We have investigated the presence of oestrogen receptor-related (ERR) mRNA in human
colorectal tumour tissues and adjacent normal mucosa by reverse transcriptase and nested …

Increased risk of colorectal cancer in patients diagnosed with breast cancer in women

Y Lu, J Segelman, A Nordgren, L Lindström, J Frisell… - Cancer …, 2016 - Elsevier
Background Epidemiological studies have shown a potential association between sex
hormones and colorectal cancer. The risk of colorectal cancer in breast cancer patients who …

Prediction of Colorectal Neoplasia by Quantitative Methylation Analysis of Estrogen Receptor Gene in Nonneoplastic Epithelium from Patients with Ulcerative Colitis

K Tominaga, S Fujii, K Mukawa, M Fujita… - Clinical cancer …, 2005 - AACR
Purpose: The incidence of colorectal neoplasia has increased among patients with
longstanding and extensive ulcerative colitis (UC). Therefore, surveillance colonoscopy has …

ESR1 and PGR gene promoter methylation and correlations with estrogen and progesterone receptors in ductal and lobular breast cancer

AD Medina-Jaime, F Reyes-Vargas… - Asian Pacific Journal …, 2014 - koreascience.kr
The aim of this work was to analyze methylation of the promoter sites of the ESR1 and PGR
genes and to determine correlations with immunohistochemical expression of estrogen and …