Human T‐lymphotropic virus 1 (HTLV‐1) pathogenesis: A systems virology study

SH Mozhgani, M Zarei‐Ghobadi… - Journal of cellular …, 2018 - Wiley Online Library
The main mechanisms of interaction between Human T‐lymphotropic virus type 1 (HTLV‐1)
and its hosts in the manifestation of the related disease including HTLV‐1 associated …

HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) versus adult T-cell leukemia/lymphoma (ATLL)

M Zarei-Ghobadi, M Sheikhi, M Teymoori-Rad… - BMC research …, 2021 - Springer
Objectives Human T cell leukemia virus-1 (HTLV-1) infection may lead to one or both
diseases including HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

Decoding pathogenesis factors involved in the progression of ATLL or HAM/TSP after infection by HTLV-1 through a systems virology study

M Zarei Ghobadi, R Emamzadeh, M Teymoori-Rad… - Virology journal, 2021 - Springer
Abstract Background Human T-cell Leukemia Virus type-1 (HTLV-1) is a retrovirus that
causes two diseases including Adult T-cell Leukemia/Lymphoma (ATLL cancer) and HTLV-1 …

HTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions

H Tarokhian, H Rahimi, A Mosavat, A Shirdel… - BMC cancer, 2018 - Springer
Background Adult T-cell leukemia/lymphoma (ATLL) is a lymphoproliferative disorder of
HTLV-1-host interactions in infected TCD4+ cells. In this study, the HTLV-1 proviral load …

Human T lymphotropic virus type 1 (HTLV-1): molecular biology and oncogenesis

P Kannian, PL Green - Viruses, 2010 - mdpi.com
Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a
proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes …

What we are learning on HTLV-1 pathogenesis from animal models

MD Dodon, J Villaudy, L Gazzolo, R Haines… - Frontiers in …, 2012 - frontiersin.org
Isolated and identified more than 30 years ago, human T cell leukemia virus type 1 (HTLV-1)
is the etiological agent of adult T cell leukemia/lymphoma, an aggressive lymphoproliferative …

Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)

S Ahmadi Ghezeldasht, DJ Blackbourn… - Critical Reviews in …, 2023 - Taylor & Francis
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy of CD4+ T
lymphocytes caused by human T lymphotropic virus type-1 (HTLV-1) infection. HTLV-1 was …

Ancient origin and molecular features of the novel human T-lymphotropic virus type 3 revealed by complete genome analysis

WM Switzer, SH Qari, ND Wolfe, DS Burke… - Journal of …, 2006 - Am Soc Microbiol
Human T-lymphotropic virus type 3 (HTLV-3) is a new virus recently identified in two primate
hunters in Central Africa. Limited sequence analysis shows that HTLV-3 is distinct from …

HTLV-1 infection and pathogenesis: New insights from cellular and animal models

G Forlani, M Shallak, RS Accolla… - International Journal of …, 2021 - mdpi.com
Since the discovery of the human T-cell leukemia virus-1 (HTLV-1), cellular and animal
models have provided invaluable contributions in the knowledge of viral infection …

HTLV‐1 oncovirus‐host interactions: From entry to the manifestation of associated diseases

S Ahmadi Ghezeldasht, SAA Shamsian… - Reviews in medical …, 2021 - Wiley Online Library
Human T lymphotropic virus type‐1 (HTLV‐1) is a well‐known human oncovirus, associated
with two life‐threatening diseases, adult T cell leukaemia/lymphoma (ATL) and HTLV‐1 …