In vitro and in vivo removal efficacy of insoluble Prussian blue in combination with calcium polystyrene sulfonate for thallium

S Jain, V Kumar, A Koul, AK Singh, N Sandal - BioMetals, 2023 - Springer
The similarities between thallium and potassium have suggested the use of calcium
polystyrene sulfonate (CPS), an oral ion exchange resin, as a potential agent against …

Relationship between physicochemical properties of Prussian blue and its efficacy as antidote against thallium poisoning

J Kravzov, C Rios, M Altagracia… - Journal of Applied …, 1993 - Wiley Online Library
In the present work we established a relationship between some physicochemical properties
of two different batches of Prussian blue (PB) and their in vivo efficacy as an antidote against …

D-penicillamine and prussian blue as antidotes against thallium intoxication in rats

C Rìos, A Monroy-Noyola - Toxicology, 1992 - Elsevier
Abstract d-penicillamine (DP) and prussian blue (PB), given alone and in combination, were
evaluated in rats as treatments against acute thallotoxicosis. Animals were poisoned by …

Elimination of thallium in rats as influenced by Prussian blue and sodium chloride

V Manninen, M Mälkönen… - Acta Pharmacologica et …, 1976 - Wiley Online Library
Abstract The effect of Prussian Blue in protecting rats against lethal doses of thallium was
investigated. Treatment with Prussian Blue increased the survival of rats from 0% to 50 …

[HTML][HTML] Toxicity and antidotal treatment by synthesized and optimized ferric (III) hexacyanoferrate (II) for thallium

V Kumar, DP Pathak, N Sandal - Bulletin of the National Research Centre, 2023 - Springer
Background The active pharmaceutical ingredient (API) of USFDA-approved
Radiogardase®-Cs capsule is ferric (III) hexacyanoferrate (II) which is commonly known as …

Additive effect of DL-penicillamine plus Prussian blue for the antidotal treatment of thallotoxicosis in rats

S Montes, G Pérez-Barrón, M Rubio-Osornio… - environmental …, 2011 - Elsevier
dl-penicillamine (DL-P) and Prussian blue (PB) given alone or in combination were tested
as possible treatments against acute thallium toxicity. Rats were intoxicated by ip injection of …

Comparative efficacy of thallium adsorption by activated charcoal, Prussian blue, and sodium polystyrene sulfonate

RS Hoffman, R Hoffman, JA Stringer… - Journal of Toxicology …, 1999 - Taylor & Francis
Background: Although Prussian blue is considered the antidote of choice for thallium
poisoning, the lack of a Food and Drug Administration-approved pharmaceutical formulation …

Effects of Prussian blue and N-acetylcysteine on thallium toxicity in mice

WJ Meggs, R Cahill-Morasco, RD Shih… - Journal of Toxicology …, 1997 - Taylor & Francis
Background: Thallium poisoning is now rare but still occurs as a result of homicide attempts.
Prussian blue's efficacy in the treatment of experimental thallium poisoning has been …

Parameters for the adsorption of thallium ions by activated charcoal and Prussian blue

PA Lehmann F, L Favari - Journal of Toxicology: Clinical Toxicology, 1984 - Taylor & Francis
Activated charcoal and Prussian blue are effective antidotes in acute thallium (Tl+)
intoxication in rats. They act by trapping any metal present in or secreted into the gut by the …

Thallium toxicity and the role of Prussian blue in therapy

RS Hoffman - Toxicological reviews, 2003 - Springer
Thallium salts have been used as medicinal agents, as key ingredients in a variety of
manufacturing processes, and as a potent rodenticide. Additionally, environmental concerns …