Introduction: Several neuroimaging techniques have been used to define in vivo markers of
pathological alterations underlying amyotrophic lateral sclerosis (ALS). Growing evidence …

Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of upper
and lower motor neurons, with variable involvement of extramotor brain regions. Currently …

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease for which a precise
cause has not yet been identified. Standard CT or MRI evaluation does not demonstrate …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative, clinically
heterogeneous syndrome pathologically overlapping with frontotemporal dementia. To date …

Introduction: In the last decade, multiparametric magnetic resonance imaging (MRI) has
achieved tremendous advances in applications to amyotrophic lateral sclerosis (ALS) to …

Amyotrophic lateral sclerosis (ALS) is now recognised to be a heterogeneous
neurodegenerative syndrome of the motor system and its frontotemporal cortical …

In the past two decades, structural and functional neuroimaging findings have greatly
modified longstanding notions regarding the pathophysiology of amyotrophic lateral …

MRI and PET studies in ALS have consistently shown patterns of functional and structural
changes considered to be the pathological signature of the disease. The constant advance …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disorder
which is incurable to date. As there are many ongoing studies with therapeutic candidates, it …

Importance of the field: With the emergence of therapeutic candidates for the incurable and
rapidly progressive neurodegenerative condition of amyotrophic lateral sclerosis (ALS), it …