Background: Cisplatin is one of the anticancer drugs used for head and neck cancers.
Although some studies have shown that cisplatin can cause ototoxicity, periodic audiometric …

BACKGROUND: Cisplatin-induced ototoxicity shows high interindividual variability and is
often accompanied by transient or permanent tinnitus. It is not possible to identify the …

Chemotherapeutic agents are known to cause multiple toxicities such as myelotoxicity,
nephrotoxicity and ototoxicity. A prospective study was carried out on 60 patients receiving …

Objective: To determine whether abnormalities in routine blood tests were associated with
increased susceptibility to hearing loss induced by cisplatin chemotherapy. Design: Cohort …

Today, with effective state-of-the-art treatment, many more cancer patients are either being
cured of their disease or are enjoying many years of near-normal life. As a result of this, long …

Cisplatin is a potent chemotherapeutic agent that is commonly used to treat a wide variety of
tumours. Although highly effective, its administration is complicated by its ototoxic effect, a …

Objective. To elucidate the incidence of cisplatin induced ototoxicity in adult patients, with a
focus on an adult population. Study Design. IRB approved retrospective study. Methods. The …

Objectives: To analyze the role of audiometry in considering change to a less ototoxic
treatment in head and neck cancer (HNC) patients. Methods: Consecutive patients …

Background Definitive cisplatin-based chemoradiation is increasingly delivered as the
treatment of choice for patients with head and neck cancer. Sensorineural hearing loss is a …

Background Cervical cancer, one of the most common cancers affecting females in South
Africa, commonly requires a cisplatin-based-treatment regimen, which has been associated …