[PDF][PDF] Geniposide Isolated from Gardeniae Fructus Induces Time-Dependent Hepatic Injury in Mice

JW Zhang, HF Chen, BM Xu, JJ Huang… - Biomedical Journal of …, 2019 - academia.edu
Geniposide Isolated from Gardeniae Fructus Induces Time-Dependent Hepatic Injury in Mice
Page 1 Copyright@ Wei-Xia Zhang | Biomed J Sci & Tech Res | BJSTR. MS.ID.003676. 16264 …

[HTML][HTML] Protective effects of geniposide and genipin against hepatic ischemia/reperfusion injury in mice

J Kim, HY Kim, SM Lee - Biomolecules & therapeutics, 2013 - ncbi.nlm.nih.gov
Geniposide is an active product extracted from the gardenia fruit, and is one of the most
widely used herbal preparations for liver disorders. This study examined the cytoprotective …

Protective effects of geniposide on hepatic ischemia/reperfusion injury

YP Rong, HT Huang, JS Liu, L Wei - Transplantation proceedings, 2017 - Elsevier
Background Geniposide (GEN) is the major ingredient of Gardenia jasminoides Ellis, which
has anti-inflammatory and anti-apoptotic activities and is widely used to treat ischemia …

Bidirectional effects of geniposide in liver injury: Preclinical evidence construction based on meta-analysis

X Zeng, J Jiang, S Liu, Q Hu, S Hu, J Zeng, X Ma… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Gardenia jasminoides J. Ellis is widely used to treat liver
diseases in traditional Chinese medicine. Geniposide, a major active constituent of …

[HTML][HTML] Dose-related liver injury of Geniposide associated with the alteration in bile acid synthesis and transportation

J Tian, J Zhu, Y Yi, C Li, Y Zhang, Y Zhao, C Pan… - Scientific reports, 2017 - nature.com
Fructus Gardenia (FG), containing the major active constituent Geniposide, is widely used in
China for medicinal purposes. Currently, clinical reports of FG toxicity have not been …

Geniposide protects against acute alcohol-induced liver injury in mice via up-regulating the expression of the main antioxidant enzymes

J Wang, Y Zhang, R Liu, X Li, Y Cui… - Canadian Journal of …, 2015 - cdnsciencepub.com
Geniposide (GP) is one of main compounds in Gardenia jasminoides Ellis, with both
medicinal and nutritional value. This study was designed to determine, for the first time, how …

Cytotoxic effect of geniposide and its metabolite genipin on HepG2 cells and mechanism

Y Ren, Y Tian, C LI, Y HE, J MA… - Chinese …, 2016 - pesquisa.bvsalud.org
Aim To compare the cytotoxicity of geni-poside (GS) and its metabolite genipin (GP) on hu-
man hepatocelluar HepG2 cells and explore the sub-stance and mechanism of …

Study on liver protection, cholagogic effect and hepatotoxicity of Gardeniae fructus

H Zhang, W Wu, F Li, W Song, Y He… - Zhongguo Zhong yao za …, 2011 - europepmc.org
Gardenia is widely used in clinical treatment to cure acute and chronic liver disease. But in
recent two decades, hepatotoxicity has been reported from gardenia and major components …

Geniposidic acid protects against D-galactosamine and lipopolysaccharide-induced hepatic failure in mice

SJ Kim, KM Kim, J Park, JH Kwak, YS Kim… - Journal of …, 2013 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Geniposidic acid (GA) is an iridoid glucoside
isolated from Gardeniae jasminoides Ellis (Rubiaceae) that has long been used to treat …

Marker genes of geniposide-induced hepatotoxicity based on genomic strategy

YZ Hu, DF Li, Y Zhang, JY Wei… - Zhongguo Zhong yao za …, 2019 - europepmc.org
The aim of this paper was to screen out relevant genes of geniposide-induced hepatotoxicity
based on genomics, in order to provide a scientific basis for the non-clinical evaluation of …