Novispirin G10-Induced Lung Toxicity in a Klebsiella pneumoniae Infection Model

KH Bartlett, PB McCray Jr… - Antimicrobial agents and …, 2003 - Am Soc Microbiol
Mammalian cathelicidins are a class of innate antimicrobial peptides isolated from
leukocytes and epithelial cells that aid host defense against bacterial infections. Synthetic …

Pretreatment with cathelicidin-BF ameliorates Pseudomonas aeruginosa pneumonia in mice by enhancing NETosis and the autophagy of recruited neutrophils and …

C Liu, J Qi, B Shan, R Gao, F Gao, H Xie… - International …, 2018 - Elsevier
Although the antimicrobial peptide cathelicidin-BF shows minimal cytotoxicity in mammalian
cells and has excellent direct killing effects on multidrug-resistant clinical pathogens such as …

[HTML][HTML] OmpA Binding Mediates the Effect of Antimicrobial Peptide LL-37 on Acinetobacter baumannii

MF Lin, PW Tsai, JY Chen, YY Lin, CY Lan - PLoS One, 2015 - journals.plos.org
Multidrug-resistant Acinetobacter baumannii has recently emerged as an important
pathogen in nosocomial infection; thus, effective antimicrobial regimens are urgently …

Cathelin‐related antimicrobial peptide differentially regulates T‐and B‐cell function

NW Kin, Y Chen, EK Stefanov, RL Gallo… - European journal of …, 2011 - Wiley Online Library
Mammalian antimicrobial peptides (AMPs) play an important role in host defense via direct
antimicrobial activity as well as immune regulation. The mouse cathelin‐related …

Antibacterial mechanism of peptide Cec4 against Acinetobacter baumannii

J Peng, H Long, W Liu, Z Wu, T Wang… - Infection and drug …, 2019 - Taylor & Francis
Background A case of Acinetobacter baumannii (A. baumannii), known as gram-negative
bacteria, causes a range of nosocomial infections. Due to the continuous detection of multi …

[HTML][HTML] A bovine myeloid antimicrobial peptide (BMAP-28) and its analogs kill pan-drug-resistant Acinetobacter baumannii by interacting with outer membrane protein …

Y Guo, M Xun, J Han - Medicine, 2018 - journals.lww.com
Antimicrobial peptides (AMPs) exhibit multiple activities against bacteria and fungi. A bovine
myeloid antimicrobial peptide (BMAP-28) belongs to the cathelicidin-derived AMPs and has …

Intrathecal application of the antimicrobial peptide CRAMP reduced mortality and neuroinflammation in an experimental model of pneumococcal meningitis

A Dörr, E Kress, R Podschun, T Pufe, SC Tauber… - Journal of Infection, 2015 - Elsevier
Antimicrobial peptides (AP) are important components of the innate immune system. Our
previous work revealed a higher mortality rate and up-regulation of proinflammatory gene …

Natural Antibodies Mediate Protection Against Acinetobacter baumannii Respiratory Infections

A Islam, LA Actis, TJ Wilson - The Journal of Infectious Diseases, 2023 - academic.oup.com
Background Acinetobacter baumannii causes a wide range of dangerous infections due to
the emergence of pandrug-resistant strains. Therefore, there is a need for alternative …

The antimicrobial peptide LL‐37 modulates the inflammatory and host defense response of human neutrophils

SM Alalwani, J Sierigk, C Herr… - European journal of …, 2010 - Wiley Online Library
The human cathelicidin antimicrobial peptide acts as an effector molecule of the innate
immune system with direct antimicrobial and immunomodulatory effects. The aim of this …

Hirudomacin: a Protein with Dual Effects of Direct Bacterial Inhibition and Regulation of Innate Immunity

Y Du, H Shi, Q Guo, C Liu, K Zhao - Applied and Environmental …, 2023 - Am Soc Microbiol
Hirudomacin (Hmc) belongs to the Macin family of antimicrobial peptides, which can be
used for bactericidal purposes in vitro by cleaving cell membranes. Although the Macin …