A number of congenital and acquired disorders require esophageal tissue replacement.
Various surgical techniques, such as gastric and colonic interposition, are standards of …

Esophageal tissue engineering is still in an early state, and ideal methods have not been
developed. Since the beginning of the 20th century, advances have been made in the …

Tissue engineering, which consists of the combination and in vivo implantation of elements
required for tissue remodeling toward a specific organ phenotype, could be an alternative for …

Abstract Treatment of esophageal cancer often requires surgical procedures that involve
removal. The current approaches to restore esophageal continuity however, are known to …

For various esophageal diseases, the search for alternative techniques for tissue repair has
led to significant developments in basic and translational research in the field of tissue …

Pathologies that involve the structure and/or function of the esophagus can be life-
threatening. The esophagus is a complex organ comprising nonredundant tissue that does …

The diseases of the esophagus include congenital defects like atresia, tracheoesophageal
fistula as well as others such as gastro-esophageal reflux disease (GERD), Barrett's …

Esophageal atresia occurs in 1 out of 3000 births. Current treatments involve esophageal
replacement by using more distal parts of the gastrointestinal tract, such as the stomach …

OBJECTIVES: We proposed to fabricate a tissue-engineered esophagus and to use it for
replacement of the abdominal esophagus. METHODS: Esophagus organoid units …

Several paediatric gastrointestinal diseases result in life-shortening organ failure. For many
of these conditions, current therapeutic options are suboptimal and may not offer a cure …